Orioles vs. Guardians Dunkel MLB Picks, Predictions and Prop Bets - Sept. 7

The Baltimore Orioles and Cleveland Guardians square off in the first of a three-game series on Monday at Oriole Park at Camden Yards, at 1:35 p.m. ET. Trevor Rogers (9-9, 4.30 ERA) will start for the Orioles, who are 69-75 this season and fifth in the AL East. Joey Cantillo (9-8, 3.81 ERA) is the expected starter for the Guardians, who are 73-71 and second in the AL Central.

The Orioles are moderate favorites on the moneyline (-139) at home over the Guardians (+115). The contest has a total set at 7.

Orioles vs. Guardians Odds, Game Time

• Game day: Monday, September 7, 2026
• Game time: 1:35 p.m. ET
• Location: Baltimore, Maryland
• Stadium: Oriole Park at Camden Yards
• Favorite: Orioles (-139)
• Underdog: Guardians (+115)
• Over/under: 7

How to Watch Orioles vs. Guardians

• TV Channel: MASN and CLEG
• Live Stream: Fubo (Watch for free)

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Orioles vs. Guardians: Betting the Moneyline

• The Orioles have gone 35-31 in games they were favored on the moneyline (winning 53% of those games).
• Cleveland has been victorious in 26, or 48.1%, of the 54 contests it has been chosen as underdogs in this season.
• Baltimore has a record of 13-10 in games when bookmakers favor them by at least -139 on the moneyline.
• This season, the Guardians have come away with a win 16 times in 28 chances when named as an underdog of at least +115 or longer on the moneyline.
• The implied moneyline probablility for this matchup gives the Orioles a 58.2% chance to win.
• The moneyline set for this matchup implies the Guardians have a 46.5% chance of coming away with a victory in the contest.

Orioles vs. Guardians: Betting the Spread & Total

• The Orioles have played in 144 games with an over/under set, and have combined with their opponents to go over the total 71 times (71-70-3).
• Cleveland and its opponents have gone over the total this season in 67 of its 144 opportunities.
• The Orioles have a 73-71-0 record against the spread this season (covering 50.7% of the time).
• The Guardians are 68-76-0 against the spread in their 144 games that had a posted line this season.