Orioles vs. Guardians Dunkel MLB Picks, Predictions and Prop Bets - Sept. 7

The Baltimore Orioles and Cleveland Guardians square off in the first of a three-game series on Monday at Oriole Park at Camden Yards, at 1:35 p.m. ET. Trevor Rogers (9-9, 4.30 ERA) gets the start for the Orioles, who are 69-74 this season and fifth in the AL East. Joey Cantillo (9-8, 3.81 ERA) is the expected starter for the Guardians, who are 72-71 and second in the AL Central.

With the Guardians (+102) visiting, the Orioles (-120) are a solid favorite on the moneyline. The game has an over/under of 8 runs.

Orioles vs. Guardians Odds, Game Time

• Game day: Monday, September 7, 2026
• Game time: 1:35 p.m. ET
• Location: Baltimore, Maryland
• Stadium: Oriole Park at Camden Yards
• Favorite: Orioles (-120)
• Underdog: Guardians (+102)
• Over/under: 8

How to Watch Orioles vs. Guardians

• TV Channel: MASN and CLEG
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Orioles vs. Guardians: Betting the Moneyline

• The Orioles have won 53% of the games this season when they were favored on the moneyline (35-31).
• Cleveland has won in 26, or 48.1%, of the 54 contests it has been named as odds-on underdogs in this year.
• Baltimore has entered 54 games this season favored by -120 or more and is 29-25 in those contests.
• The Guardians have a win-loss record of 24-21 when favored by +102 or worse by oddsmakers this year.
• Based on this matchup's moneyline, the Orioles have an implied win probability of 54.5%.
• The Guardians have an implied victory probability of 49.5% according to the moneyline set for this matchup.

Orioles vs. Guardians: Betting the Spread & Total

• The Orioles have played in 143 games with a set over/under, and have combined with their opponents to go over the total 71 times (71-69-3).
• Cleveland and its opponents have hit the over in 67 of its 143 games with a total this season.
• The Orioles have a 73-70-0 record ATS this season (covering 51% of the time).
• The Guardians have posted a record of 68-75-0 against the spread this season.