Louisville vs. Ohio Dunkel Predictions & Vegas Odds - Nov. 15

The No. 12 Louisville Cardinals (3-0) host the Ohio Bobcats (1-2) at KFC Yum! Center, tipping off at 12 p.m. ET on Saturday, November 15, 2025. The Cardinals are 30.5-point favorites in the game. The matchup has an over/under of 174.5 points.

In its most recent game on Tuesday, Louisville secured a 96-88 victory over Kentucky. Mikel Brown Jr. scored a team-high 29 points for Louisville in the win. Ohio enters this matchup on the heels of a 90-60 loss to Saint Mary's (CA) on Tuesday. Jackson Paveletzke totaled 19 points, three rebounds and four assists for Ohio.

Louisville vs. Ohio Odds and Game Time

• When: Saturday, November 15, 2025 at 12 p.m. ET
• Where: KFC Yum! Center in Louisville, Kentucky
• Spread favorite: Louisville -30.5
• Moneyline favorite: Louisville -50000
• Moneyline underdog: Ohio +4000
• Over/Under: 174.5 points

How to watch Louisville vs. Ohio

• TV Channel: CW (WGN - Chicago)
• Live Stream: Fubo
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Louisville vs. Ohio

• Louisville played one game with over 174.5 points scored, its current matchup's point total, last season.
• Four of Ohio's 31 games last season had more than 174.5 total points scored.
• The Cardinals and the Bobcats combined to average 16.2 fewer points per game a season ago than the over/under of 174.5 set for this matchup.
• Opponents of these teams averaged a combined 146 points per game last season, 28.5 fewer than the point total for this matchup.
• Louisville's average point total in matchups last year was 148, 26.5 points less than the total in this game.
• The average over/under in Ohio's games in 2024 was 18.2 fewer points than the point total of 174.5 in this game.

Betting the Spread: Louisville vs. Ohio

• Louisville won 20 games against the spread last season, while failing to cover 15 times.
• Ohio went 12-19-0 ATS last season.
• Louisville was 8-9 against the spread, and 14-3 overall, at home last season.
• On the road last season, Ohio was 3-10 overall and 3-10 against the spread.

Betting the Moneyline: Louisville vs. Ohio

• Louisville finished with a 22-5 record in games it was favored on the moneyline last season (winning 81.5% of those games).
• The Cardinals never played a game last season with moneyline odds of -50000 or shorter.
• The implied moneyline probability in this matchup gives Louisville a 99.8% chance to win.
• Ohio won two of the seven games it played as underdogs last season.
• The Bobcats were not a bigger underdog last season than the +4000 moneyline set for this game.
• The oddsmakers' moneyline implies a 2.4% chance of a victory for Ohio.