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Angels vs. Athletics Dunkel MLB Picks, Predictions and Prop Bets - May 21

21 May 2026 By Data Skrive

The Los Angeles Angels host the Athletics at 9:38 p.m. ET on Thursday. Jose Soriano (6-3, 2.41 ERA) gets the start for the Angels, who are 17-33 this season and fifth in the AL West. Luis Severino (2-5, 4.45 ERA) is expected to start for the Athletics, who are 25-24 and first in the AL West.

With moneyline odds of -110 for the Angels and -109 for the Athletics, this could be a close contest. The game has an over/under of 8 runs.

Angels vs. Athletics Odds, Game Time

  • Game day: Thursday, May 21, 2026
  • Game time: 9:38 p.m. ET
  • Location: Anaheim, California
  • Stadium: Angel Stadium
  • Favorite: Angels (-110)
  • Underdog: Athletics (-109)
  • Over/under: 8

How to Watch Angels vs. Athletics

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Angels vs. Athletics: Betting the Moneyline

  • The Angels have been the moneyline favorite 10 total times this season. They've finished 4-6 in those games.
  • The Athletics have won in 18, or 56.2%, of the 32 contests they have been named as odds-on underdogs in this year.
  • This season, the Angels have won four of their 10 games, or 40%, when favored by at least -110 on the moneyline.
  • This year, the Athletics have won 17 of 31 games when listed as at least -109 or better on the moneyline.
  • The Angels have a 52.4% chance to win this game based on the moneyline's implied probability.
  • The Athletics have an implied victory probability of 52.2% according to the moneyline set for this matchup.

Angels vs. Athletics: Betting the Spread & Total

  • The Angels have played in 50 games with an over/under set, and have combined with their opponents to go over the total 24 times (24-25-1).
  • The Athletics and their opponents have hit the over in 23 of their 49 games with a total this season.
  • The Angels are 23-27-0 against the spread this season.
  • The Athletics have an against the spread mark of 27-22-0 in 49 games with a line this season.
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