Royals vs. Guardians Dunkel MLB Picks, Predictions and Prop Bets - May 6

The Cleveland Guardians will aim to snap a three-game losing streak when visiting the Kansas City Royals at 7:40 p.m. ET on Wednesday. Cole Ragans (1-4, 5.29 ERA) will start for the Royals, who are 17-19 this season and third in the AL Central. Joey Cantillo (1-1, 3.67 ERA) is starting for the Guardians, who are 18-19 and second in the AL Central.

The Royals are moderate favorites on the moneyline (-134) at home over the Guardians (+113). The game's over/under is 7.5.

Royals vs. Guardians Odds, Game Time

• Game day: Wednesday, May 6, 2026
• Game time: 7:40 p.m. ET
• Location: Kansas City, Missouri
• Stadium: Kauffman Stadium
• Favorite: Royals (-134)
• Underdog: Guardians (+113)
• Over/under: 7.5

How to Watch Royals vs. Guardians

• TV Channel: ROYL and CLEG
• Live Stream: Fubo (Watch for free)

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Royals vs. Guardians: Betting the Moneyline

• The Royals have gone 10-7 in games they were listed as the moneyline favorite (winning 58.8% of those games).
• Cleveland has been underdogs in 19 games this season and has come away with the win nine times (47.4%) in those contests.
• Kansas City is 4-3 this season when entering a game favored by -134 or more on the moneyline.
• This year, the Guardians have won five of 11 games when listed as at least +113 or worse on the moneyline.
• The Royals have an implied moneyline win probability of 57.3% in this matchup.
• The moneyline set for this matchup implies the Guardians have a 46.9% chance of coming away with a victory in the contest.

Royals vs. Guardians: Betting the Spread & Total

• The Royals have had an over/under set by bookmakers 36 times, and have combined with opponents to go over the total in 15 of those games (15-21-0).
• Cleveland's games have gone over the total in 18 of its 37 chances.
• The Royals have a 17-19-0 record ATS this season (covering 47.2% of the time).
• The Guardians are 19-18-0 against the spread in their 37 games with a line set by sportsbooks this season.