Chiefs vs. Chargers Week 6 Dunkel NFL Picks, Predictions and Odds

Having won four in a row, the Kansas City Chiefs (4-0) will face the Los Angeles Chargers (0-5). The Chiefs are solid favorites, expected to win by at least a touchdown (currently -8.5). The game has an over/under of 42.5 points.

The Chiefs have the seventh-ranked defense this year (19.3 points allowed per game), and they've been more effective on offense, ranking fifth-best with 29.5 points per game. The Chargers rank 25th with 292.8 total yards per game on offense, and they rank 10th with 311.6 total yards surrendered per contest on the defensive side of the ball.

Chiefs vs. Chargers Odds and Game Time

• Date: Sunday, October 18, 2026
• Time: 4:25 p.m. ET
• City: Kansas City, Missouri
• Venue: GEHA Field at Arrowhead Stadium
• Total: 42.5 points
• Spread: Chiefs -8.5
• Moneyline: Chiefs (-500), Chargers (+380)

How to watch Chiefs vs. Chargers

• TV Channel: CBS

Betting the Over/Under: Chiefs vs. Chargers

• In two games this season, the Chiefs and their opponents have combined to put up more than 42.5 points.
• This season, games featuring the Chiefs have gone over the point total twice.
• The Chargers and their opponents have scored more than 42.5 combined points once this season.
• So far this year, just one Los Angeles game has gone over the point total.
• The two teams combine to score 46.3 points per game, 3.8 more points than this matchup's total.
• Opponents of these teams average 45.1 combined points per game, 2.6 more points than this matchup's total.

Betting the Spread: Chiefs vs. Chargers

• Kansas City has covered twice in four matchups with a spread this season.
• Kansas City has been favored by 8.5 points or more once this season, and covered the spread.
• The Chargers are winless against the spread this season (0-4-1).

Betting the Moneyline: Chiefs vs. Chargers

• Kansas City has won all four of the games it has been listed as the moneyline favorite this season.
• This season, the Chargers have been listed as the underdog in three games and failed to win any of those contests.
• Kansas City has played as a moneyline favorite of -500 or shorter in just one game this season, which it won.
• Los Angeles has not entered a game this season with longer moneyline odds than +380.
• Based on this matchup's moneyline, the Chiefs have an implied win probability of 83.3%.

Dunkel Prediction for Chiefs vs. Chargers

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