Iowa State vs. Tennessee State Dunkel Predictions & Vegas Odds - First Round

The No. 15 Tennessee State Tigers (23-9) are 24.5-point underdogs to advance to the second round of the NCAA Tournament when they play the No. 2 Iowa State Cyclones (27-7) on Friday. Here are some insights into this 2-15 matchup in the Midwest Region bracket that tips off at 2:50 p.m. ET, live on CBS. The matchup's point total is 149.5.

Iowa State enters this matchup following an 82-80 loss to Arizona on Friday. Milan Momcilovic scored a team-leading 28 points for Iowa State in the loss. Tennessee State heads into this game on the heels of a 93-67 victory over Morehead State on Saturday. Antoine Lorick III scored 18 points in Tennessee State's win, leading the team.

Iowa State vs. Tennessee State Odds and Game Time

• When: Friday, March 20, 2026 at 2:50 p.m. ET
• Where: Enterprise Center in St. Louis, Missouri
• Spread favorite: Iowa State -24.5
• Moneyline favorite: Iowa State -11111
• Moneyline underdog: Tennessee State +2520
• Over/Under: 149.5 points

How to watch Iowa State vs. Tennessee State

• TV Channel: CBS
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Iowa State vs. Tennessee State

• A total of 15 of Iowa State's games this season have gone over Friday's over/under of 149.5 points.
• In Tennessee State's 29 games this season, 13 finished with more combined points than Friday's total of 149.5.
• The point total for the matchup of 149.5 is 12.8 points fewer than the combined points per game averages for the Cyclones (81.8 points per game) and the Tigers (80.5 points per game).
• These two teams give up a combined 138.4 points per game, 11.1 less than this contest's over/under.
• This season the average over/under for Iowa State's games is 146.9 points, 2.6 fewer than the over/under of 149.5 set for this contest.
• The over/under for this contest is 4.4 points lower than the average over/under in Tennessee State's games this season of 153.9.

Betting the Spread: Iowa State vs. Tennessee State

• Against the spread, Iowa State is 20-14-0 this year.
• So far this season, the Cyclones have been installed as favorites by a 24.5-point margin or more seven times and are 3-4 ATS in those games.
• Tennessee State is 18-11-0 against the spread this season.
• This year, the Tigers won ATS in their only game as an underdog of 24.5 points or more.
• At home this year, Iowa State is 16-1 overall and 9-8 against the spread.
• At home, as a 24.5-point favorite or more, Iowa State is 3-4 ATS.
• This year in away games, Tennessee State is 10-6 against the spread and 9-7 overall.

Betting the Moneyline: Iowa State vs. Tennessee State

• Iowa State has won 24, or 82.8%, of the 29 games it has played as the moneyline favorite this season.
• The Cyclones have been at least a -11111 moneyline favorite three times this season and won each of those games.
• The implied probability of a win from Iowa State, based on the moneyline, is 99.1%.
• Tennessee State has been a moneyline underdog in 11 games this season and has come away with the win six times (54.5%) in those contests.
• The Tigers have played as an underdog of +2520 or more just one time this year and came away with a loss in that game.
• The moneyline set for this matchup implies Tennessee State has a 3.8% chance of coming away with a victory in the contest.