Colts vs. Commanders Week 4 Dunkel NFL Picks, Predictions and Odds

This week, the NFL travels to London, England as the Indianapolis Colts (1-2) face the Washington Commanders (1-2) at Tottenham Hotspur Stadium on Sunday, October 4, 2026. The Colts are favorites in this one, with the spread sitting at 4.5 points. The expected point total for the matchup is set at 46.5.

The Colts sport the 15th-ranked scoring offense this year (24.0 points per game), and they've been worse on defense, ranking fourth-worst with 30.3 points allowed per game. The Commanders' defense has been a bottom-five unit in scoring defense this season, surrendering 30.7 points per game, which ranks second-worst in the NFL. Offensively, they rank 13th with 25.0 points per contest.

Colts vs. Commanders Odds and Game Time

• Date: Sunday, October 4, 2026
• Time: 9:30 a.m. ET
• City: London, England
• Venue: Tottenham Hotspur Stadium
• Total: 46.5 points
• Spread: Colts -4.5
• Moneyline: Colts (-205), Commanders (+170)

How to watch Colts vs. Commanders

• TV Channel: NFL Network

Betting the Over/Under: Colts vs. Commanders

• The Colts and their opponents have scored a combined total of more than 46.5 points twice this season (over three games).
• This season, games featuring the Colts have hit the over twice.
• The Commanders have combined with their opponent to score more than 46.5 points only twice this season.
• So far this year, each Washington game has gone over the point total.
• These two teams score a combined 49 points per game, 2.5 more points than this matchup's over/under.
• These teams surrender 61 points per game combined, 14.5 more points than this matchup's total.

Betting the Spread: Colts vs. Commanders

• Indianapolis has won two games against the spread this season.
• The Commanders have covered twice in three chances against the spread this year.
• Washington has covered the spread twice this year (2-1 ATS) when playing as at least 4.5-point underdogs.

Betting the Moneyline: Colts vs. Commanders

• Indianapolis is playing as the moneyline favorite in its first game this season.
• This season, the Commanders have been the underdog three times and won one of those games.
• Indianapolis has not yet played as a moneyline favorite of -205 or shorter.
• Washington has a record of 1-1 when it is set as an underdog of +170 or more by oddsmakers this season.
• Based on this game's moneyline, the Colts' implied win probability is 67.2%.

Dunkel Prediction for Colts vs. Commanders

For more expert NFL picks, visit our Dunkel Index NFL Picks and Predictions.