Astros vs. Athletics Dunkel MLB Picks, Predictions and Prop Bets - Aug. 22

The Athletics will aim to stop a five-game losing streak when visiting the Houston Astros at 7:10 p.m. ET on Saturday. Hunter Brown (3-3, 3.67 ERA) gets the start for the Astros, who are 65-64 this season and first in the AL West. Jacob Lopez (5-4, 5.22 ERA) is the expected starter for the Athletics, who are 49-80 and fifth in the AL West.

The Athletics (+159) are on the road versus the favored Astros (-181). The game's total is 8.5.

Astros vs. Athletics Odds, Game Time

• Game day: Saturday, August 22, 2026
• Game time: 7:10 p.m. ET
• Location: Houston, Texas
• Stadium: Daikin Park
• Favorite: Astros (-181)
• Underdog: Athletics (+159)
• Over/under: 8.5

How to Watch Astros vs. Athletics

• TV Channel: SCHN and NBCS-CA
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Astros vs. Athletics: Betting the Moneyline

• The Astros are 27-28 in games they were favored on the moneyline (winning 49.1% of those games).
• The Athletics have won in 33, or 35.5%, of the 93 contests they have been named as odds-on underdogs in this year.
• The Astros have a record of 2-4 when they're favored by -181 or more by sportsbooks this season.
• This year, the Athletics have won four of 15 games when listed as at least +159 or better on the moneyline.
• The implied moneyline probablility in this matchup gives the Astros a 64.4% chance to win.
• The Athletics have an implied victory probability of 38.6% according to the moneyline set by sportsbooks for this matchup.

Astros vs. Athletics: Betting the Spread & Total

• The Astros have played in 129 games with an over/under set, and have combined with their opponents to go over the total 67 times (67-55-7).
• Games involving the Athletics have gone over the total set by oddsmakers in 63 of 129 chances this season.
• The Astros have a 65-64-0 record against the spread this season (covering 50.4% of the time).
• In 129 games with a line this season, the Athletics have a mark of 58-71-0 against the spread.