Astros vs. Athletics Dunkel MLB Picks, Predictions and Prop Bets - Aug. 21

The Houston Astros and Athletics clash on Friday at 8:10 p.m. ET, beginning a three-game series at Daikin Park. Hayden Wesneski (2-1, 5.16 ERA) gets the start for the Astros, who are 64-64 this season and first in the AL West. J.T. Ginn (8-7, 3.53 ERA) is expected to start for the Athletics, who are 49-79 and fifth in the AL West.

The sportsbooks have spoken, making the Astros (-182) a moderate moneyline favorite to defeat the Athletics (+159) at home. The total for this contest is set at 8.

Astros vs. Athletics Odds, Game Time

• Game day: Friday, August 21, 2026
• Game time: 8:10 p.m. ET
• Location: Houston, Texas
• Stadium: Daikin Park
• Favorite: Astros (-182)
• Underdog: Athletics (+159)
• Over/under: 8

How to Watch Astros vs. Athletics

• TV Channel: SCHN and NBCS-CA
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Astros vs. Athletics: Betting the Moneyline

• The Astros have put together a 26-28 record in games they were favored on the moneyline (winning 48.1% of those games).
• The Athletics have come away with 33 wins in the 92 contests they have been listed as the underdogs in this season.
• This season, the Astros have won one of their five games when favored by at least -182 on the moneyline.
• This season, the Athletics have come away with a win four times in 15 chances when named as an underdog of at least +159 or worse on the moneyline.
• The Astros have a 64.5% chance to win this matchup based on the moneyline's implied probability.
• The Athletics have an implied victory probability of 38.6% according to the moneyline set by oddsmakers for this matchup.

Astros vs. Athletics: Betting the Spread & Total

• The Astros have combined with their opponents to hit the over on the total 67 times this season for a 67-54-7 record against the over/under.
• Games involving the Athletics have gone over the total set by bookmakers in 63 of 128 chances this season.
• The Astros have covered 50% of their games this season, going 64-64-0 against the spread.
• The Athletics have posted a record of 58-70-0 against the spread this season.