Duke vs. Michigan State Dunkel Predictions & Vegas Odds - Nov. 10

The No. 2 Duke Blue Devils (2-0) hit the court against the No. 6 Michigan State Spartans (2-0) as 6.5-point favorites on Tuesday, November 10, 2026 at 7 p.m. ET on ESPN. The point total is 148.5 in the matchup.

In its most recent outing on Thursday, Duke claimed a 113-52 victory over Coastal Carolina. In Duke's win, Patrick Ngongba II led the way with a team-high 28 points (adding nine rebounds and one assist). Michigan State won its last outing 91-61 against Toledo on Thursday. Jasiah Jervis recorded 16 points, five rebounds and one assist for Michigan State.

Duke vs. Michigan State Odds and Game Time

• When: Tuesday, November 10, 2026 at 7 p.m. ET
• Where: United Center in Chicago, Illinois
• Spread favorite: Duke -6.5
• Moneyline favorite: Duke -278
• Moneyline underdog: Michigan State +224
• Over/Under: 148.5 points

How to watch Duke vs. Michigan State

• TV Channel: ESPN
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Duke vs. Michigan State

• Duke's games went over 148.5 points scored, its current matchup's over/under, 17 times (out of 38) last season.
• Last season, 15 of Michigan State's 35 games had a combined total of more than 148.5 points scored.
• The Blue Devils and the Spartans combined to average 11.9 more points per game a season ago than the over/under of 148.5 set for this game.
• Opponents of the two teams averaged a combined 16.6 fewer points per game (131.9) last season than this game's total of 148.5 points.
• The average point total in Duke's games last year was 3.2 fewer points than the total of 148.5 in this matchup.
• Michigan State's games in 2025 averaged an over/under of 147.1 points, 1.4 fewer than the point total in this matchup.

Betting the Spread: Duke vs. Michigan State

• Duke went 20-18-0 ATS last season.
• When playing as at least 6.5-point favorites last season, the Blue Devils had an ATS record of 17-17.
• Michigan State put together an 18-17-0 record against the spread last year.
• The Spartans were an underdog by 6.5 points or more two times last year, and covered the spread in one of those contests.
• Michigan State was 8-9 against the spread, and 15-2 overall, at home last year.
• At home last year, as a 6.5-point underdog or greater, Michigan State was 5-7 ATS.
• On the road last season, Duke was 10-1 overall and 8-3 against the spread.
• Last year, as a 6.5-point favorite or more on the road, Duke was 6-3 ATS.

Betting the Moneyline: Duke vs. Michigan State

• Duke won 31 of the 34 games it was the moneyline favorite last season (91.2%).
• When they played as a moneyline favorite with odds of -278 or shorter, the Blue Devils had a 29-2 record (winning 93.5% of their games).
• Duke has a 73.5% chance to win this matchup based on the moneyline's implied probability.
• Michigan State was underdogs in seven games last season and won two (28.6%) of those contests.
• The Spartans played as an underdog of +224 or more twice last season and split those games.
• Michigan State has a 30.9% chance to win this game based on the implied probability of the moneyline.