Guardians vs. Nationals Dunkel MLB Picks, Predictions and Prop Bets - May 27

James Wood takes a two-game homer streak into the Washington Nationals' game against the Cleveland Guardians at 1:10 p.m. ET on Wednesday, at Progressive Field. Gavin Williams (7-3, 3.25 ERA) will start for the Guardians, who are 32-25 this season and first in the AL Central. Miles Mikolas (1-3, 6.17 ERA) is starting for the Nationals, who are 29-27 and second in the NL East.

With the Nationals (+156) visiting, the Guardians (-188) are a solid favorite on the moneyline. The over/under for this contest is set at 8.

Guardians vs. Nationals Odds, Game Time

• Game day: Wednesday, May 27, 2026
• Game time: 1:10 p.m. ET
• Location: Cleveland, Ohio
• Stadium: Progressive Field
• Favorite: Guardians (-188)
• Underdog: Nationals (+156)
• Over/under: 8

How to Watch Guardians vs. Nationals

• TV Channel: CLEG and NATS
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Guardians vs. Nationals: Betting the Moneyline

• The Guardians have won 56.2% of the games this season when they were the moneyline favorite (18-14).
• Washington has been victorious in 28, or 51.9%, of the 54 contests it has been chosen as underdogs in this season.
• Cleveland has not entered a game this season with shorter moneyline odds than -188.
• The Nationals have a mark of 5-7 in contests where bookmakers favor them by +156 or worse on the moneyline.
• The Guardians have an implied moneyline win probability of 65.3% in this game.
• The Nationals have an implied victory probability of 39.1% according to the moneyline set for this matchup.

Guardians vs. Nationals: Betting the Spread & Total

• The Guardians have played in 57 games with a set over/under, and have combined with their opponents to go over the total 28 times (28-29-0).
• Washington's games have gone over the total in 35 of its 56 chances.
• The Guardians have covered 54.4% of their games this season, going 31-26-0 against the spread.
• The Nationals are 36-20-0 against the spread in their 56 games with a line set by sportsbooks this season.