Guardians vs. Nationals Dunkel MLB Picks, Predictions and Prop Bets - May 26

Curtis Mead leads the Washington Nationals into a matchup against the Cleveland Guardians, after homering twice in a 10-2 victory over the Guardians, at 6:10 p.m. ET on Tuesday. Joey Cantillo (4-1, 3.05 ERA) will start for the Guardians, who are 32-24 this season and first in the AL Central. Cade Cavalli (2-3, 3.86 ERA) is expected to start for the Nationals, who are 28-27 and second in the NL East.

The Guardians (-137) are moneyline favorites at home over the Nationals (+115). The game's total is set at 7.5.

Guardians vs. Nationals Odds, Game Time

• Game day: Tuesday, May 26, 2026
• Game time: 6:10 p.m. ET
• Location: Cleveland, Ohio
• Stadium: Progressive Field
• Favorite: Guardians (-137)
• Underdog: Nationals (+115)
• Over/under: 7.5

How to Watch Guardians vs. Nationals

• TV Channel: CLEG and NATS
• Live Stream: Fubo (Watch for free)

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Guardians vs. Nationals: Betting the Moneyline

• The Guardians have won 18 of the 31 games they were favored on the moneyline this season (58.1%).
• Washington has come away with 27 wins in the 53 contests it has been listed as the underdogs in this season.
• Cleveland is 9-5 this season when entering a game favored by -137 or more on the moneyline.
• This season, the Nationals have come away with a win 22 times in 38 chances when named as an underdog of at least +115 or longer on the moneyline.
• The implied moneyline probablility in this matchup gives the Guardians a 57.8% chance to win.
• Oddsmakers have implied with the moneyline set for this matchup that the Nationals have a 46.5% chance of pulling out a win.

Guardians vs. Nationals: Betting the Spread & Total

• The Guardians have combined with opponents to hit the over on the total 27 times this season for a 27-29-0 record against the over/under.
• Washington and its opponents have gone over the total this season in 34 of its 55 opportunities.
• The Guardians have put together a 31-25-0 record ATS this season (covering 55.4% of the time).
• The Nationals have posted a record of 35-20-0 against the spread this season.