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Guardians vs. Cardinals Dunkel MLB Picks, Predictions and Prop Bets - April 14

14 April 2026 By Data Skrive

The Cleveland Guardians visit the St. Louis Cardinals at 7:45 p.m. ET on Tuesday, featuring two top-10 sluggers. Chase DeLauter has five homers (seventh in league) for the Guardians, and Jordan Walker ranks first with eight long balls for the Cardinals. Joey Cantillo (1-0, 2.45 ERA) will start for the Guardians, who are 10-7 this season and first in the AL Central. Michael McGreevy (1-1, 2.16 ERA) is starting for the Cardinals, who are 8-8 and fourth in the NL Central.

Despite playing away from their home ballpark, the Guardians are favored to win (-120) over the Cardinals (+100). The over/under for this contest is set at 8.5.

Guardians vs. Cardinals Odds, Game Time

  • Game day: Tuesday, April 14, 2026
  • Game time: 7:45 p.m. ET
  • Location: St. Louis, Missouri
  • Stadium: Busch Stadium
  • Favorite: Guardians (-120)
  • Underdog: Cardinals (+100)
  • Over/under: 8.5

How to Watch Guardians vs. Cardinals

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Guardians vs. Cardinals: Betting the Moneyline

  • The Guardians have been favored on the moneyline three total times this season. They've finished 2-1 in those games.
  • St. Louis has been victorious in seven, or 50%, of the 14 contests it has been chosen as underdogs in this season.
  • Cleveland has played as favorites of -120 or more once this season and won that game.
  • This year, the Cardinals have won five of 11 games when listed as at least +100 or worse on the moneyline.
  • The Guardians have a 54.5% chance to win this matchup based on the moneyline's implied probability.
  • The Cardinals have an implied victory probability of 50% according to the moneyline set for this matchup.

Guardians vs. Cardinals: Betting the Spread & Total

  • The Guardians have combined with opponents to go over the total eight times this season for an 8-9-0 record against the over/under.
  • So far this season, St. Louis and its opponents have hit the over in eight of its 16 games with a total.
  • The Guardians have put together an 11-6-0 record ATS this season (covering 64.7% of the time).
  • In 16 games with a line this season, the Cardinals have a mark of 7-9-0 against the spread.
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