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Guardians vs. Cardinals Dunkel MLB Picks, Predictions and Prop Bets - April 13

13 April 2026 By Data Skrive

Chase DeLauter and Jordan Walker go head-to-head in a battle between top-10 sluggers when the Cleveland Guardians and St. Louis Cardinals play on Monday at 7:45 p.m. ET. DeLauter has five homers (fourth in league) for the Guardians, and Walker ranks first with seven dingers for the Cardinals. Gavin Williams (1-1, 2.04 ERA) gets the start for the Guardians, who are 9-7 this season and first in the AL Central. Matthew Liberatore (0-0, 3.38 ERA) is the expected starter for the Cardinals, who are 8-7 and fourth in the NL Central.

The moneyline odds for the Guardians (-119) versus the Cardinals (-100) indicate a tight game. The game's total is 8.

Guardians vs. Cardinals Odds, Game Time

  • Game day: Monday, April 13, 2026
  • Game time: 7:45 p.m. ET
  • Location: St. Louis, Missouri
  • Stadium: Busch Stadium
  • Favorite: Guardians (-119)
  • Underdog: Cardinals (-100)
  • Over/under: 8

How to Watch Guardians vs. Cardinals

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Guardians vs. Cardinals: Betting the Moneyline

  • The Guardians have been listed as the moneyline favorite just two other times so far this season, and they split the two games.
  • St. Louis has won in seven, or 53.8%, of the 13 contests it has been named as odds-on underdogs in this year.
  • Cleveland has played as favorites of -119 or more twice this season and split those games.
  • The Cardinals have a win-loss record of 5-5 when favored by -100 or worse by oddsmakers this year.
  • The implied moneyline probablility for this matchup gives the Guardians a 54.3% chance to win.
  • The moneyline set for this matchup implies the Cardinals have a 50% chance of walking away with the win.

Guardians vs. Cardinals: Betting the Spread & Total

  • The Guardians have played in 16 games with a set over/under, and have combined with their opponents to go over the total seven times (7-9-0).
  • St. Louis' games have gone over the total in seven of its 15 chances.
  • The Guardians have a 10-6-0 record against the spread this season (covering 62.5% of the time).
  • In 15 games with a line this season, the Cardinals have a mark of 7-8-0 against the spread.
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