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Guardians vs. Angels Dunkel MLB Picks, Predictions and Prop Bets - May 11

11 May 2026 By Data Skrive

The Cleveland Guardians host the Los Angeles Angels to open a three-game series at Progressive Field, with first pitch at 6:10 p.m. ET on Monday. Joey Cantillo (2-1, 3.43 ERA) gets the start for the Guardians, who are 21-21 this season and first in the AL Central. The Angels, who are 16-25 and fourth in the AL West, have yet to name a starter.

Sportsbooks have made the Guardians a decent moneyline favorite (-173) at home over the Angels (+144). The game has an over/under set at 7.5 runs.

Guardians vs. Angels Odds, Game Time

  • Game day: Monday, May 11, 2026
  • Game time: 6:10 p.m. ET
  • Location: Cleveland, Ohio
  • Stadium: Progressive Field
  • Favorite: Guardians (-173)
  • Underdog: Angels (+144)
  • Over/under: 7.5

How to Watch Guardians vs. Angels

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Guardians vs. Angels: Betting the Moneyline

  • The Guardians have won 47.6% of the games this season when they were favored on the moneyline (10-11).
  • Los Angeles has come away with 12 wins in the 32 contests it has been listed as the underdogs in this season.
  • Cleveland has not been bigger favorites this season than the -173 moneyline set for this game.
  • This season, the Angels have come away with a win five times in 10 chances when named as an underdog of at least +144 or longer on the moneyline.
  • The Guardians have an implied moneyline win probability of 63.4% in this game.
  • The Angels have an implied victory probability of 41% according to the moneyline set for this matchup.

Guardians vs. Angels: Betting the Spread & Total

  • The Guardians have had an over/under set by bookmakers 42 times, and have combined with opponents to go over the total in 21 of those games (21-21-0).
  • So far this season, Los Angeles and its opponents have hit the over in 19 of its 41 games with a total.
  • The Guardians have a 23-19-0 record ATS this season.
  • The Angels are 20-21-0 against the spread in their 41 games that had a posted line this season.
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