Guardians vs. Orioles Dunkel MLB Picks, Predictions and Prop Bets - April 16

The Cleveland Guardians have dropped two games in a row as they ready to take on the Baltimore Orioles, who have also dropped two in a row. Thursday's outing at Progressive Field begins at 6:10 p.m. ET. Parker Messick (2-0, 0.51 ERA) will start for the Guardians, who are 10-9 this season and second in the AL Central. Shane Baz (0-1, 4.50 ERA) is the expected starter for the Orioles, who are 9-9 and third in the AL East.

At home, the Guardians are favored to win on the moneyline (-126) over the Orioles (+106). The game's over/under is set at 8.

Guardians vs. Orioles Odds, Game Time

• Game day: Thursday, April 16, 2026
• Game time: 6:10 p.m. ET
• Location: Cleveland, Ohio
• Stadium: Progressive Field
• Favorite: Guardians (-126)
• Underdog: Orioles (+106)
• Over/under: 8

How to Watch Guardians vs. Orioles

• TV Channel: CLEG and MASN
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Guardians vs. Orioles: Betting the Moneyline

• The Guardians have won two of the four games they were favored on the moneyline this season (50%).
• Baltimore has won in one of the four contests it has been named as odds-on underdogs in this year.
• Cleveland has played as favorites of -126 or more once this season and lost that game.
• The Orioles have played as an underdog of +106 or more just one time this year and came away with a loss in that game.
• Based on this game's moneyline, the Guardians' implied win probability is 55.8%.
• The moneyline set for this matchup implies the Orioles have a 48.5% chance of coming away with a victory in the contest.

Guardians vs. Orioles: Betting the Spread & Total

• The Guardians have played in 19 games with set over/under, and have combined with opponents to go over the total nine times (9-10-0).
• Baltimore and its opponents have hit the over in 10 of its 18 games with a total this season.
• The Guardians have an 11-8-0 record against the spread this season (covering 57.9% of the time).
• The Orioles have an against the spread mark of 7-11-0 in 18 games with a line this season.