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Reds vs. Cardinals Dunkel MLB Picks, Predictions and Prop Bets - May 23

22 May 2026 By Data Skrive

The Cincinnati Reds and St. Louis Cardinals square off in the first of a three-game series on Saturday at Great American Ball Park, at 1:10 p.m. ET. Chris Paddack (0-5, 7.07 ERA) will start for the Reds, who are 26-24 this season and fifth in the NL Central. Kyle Leahy (5-3, 3.94 ERA) is starting for the Cardinals, who are 28-21 and third in the NL Central.

The moneyline odds for the Reds (-112) versus the Cardinals (-104) indicate a tight game. The game's total is 10.

Reds vs. Cardinals Odds, Game Time

  • Game day: Saturday, May 23, 2026
  • Game time: 1:10 p.m. ET
  • Location: Cincinnati, Ohio
  • Stadium: Great American Ball Park
  • Favorite: Reds (-112)
  • Underdog: Cardinals (-104)
  • Over/under: 10

How to Watch Reds vs. Cardinals

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Reds vs. Cardinals: Betting the Moneyline

  • The Reds have gone 9-7 in games they were favored on the moneyline (winning 56.2% of those games).
  • St. Louis has been victorious in 24, or 58.5%, of the 41 contests it has been chosen as underdogs in this season.
  • Cincinnati has a record of 8-6 in games when bookmakers favor them by at least -112 on the moneyline.
  • This year, the Cardinals have won 21 of 38 games when listed as at least -104 or worse on the moneyline.
  • Based on this contest's moneyline, the Reds' implied win probability is 52.8%.
  • The moneyline set for this matchup implies the Cardinals have a 51% chance of walking away with the win.

Reds vs. Cardinals: Betting the Spread & Total

  • The Reds have played in 50 games with an over/under set, and have combined with their opponents to go over the total 31 times (31-18-1).
  • St. Louis and its opponents have gone over the total this season in 20 of its 49 opportunities.
  • The Reds have put together a 30-20-0 record ATS this season (covering 60% of the time).
  • The Cardinals are 30-19-0 against the spread in their 49 games with a line set by sportsbooks this season.
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