Reds vs. Giants Dunkel MLB Picks, Predictions and Prop Bets - April 16

The Cincinnati Reds will look to Sal Stewart, riding a two-game homer streak, versus the San Francisco Giants at 12:40 p.m. ET on Thursday, at Great American Ball Park. Chase Burns (1-1, 3.31 ERA) gets the start for the Reds, who are 11-7 this season and first in the NL Central. Landen Roupp (2-1, 3.24 ERA) is the expected starter for the Giants, who are 6-12 and fifth in the NL West.

With the Giants (+109) visiting, the Reds (-130) are a solid favorite on the moneyline. The over/under for this contest is set at 8.

Reds vs. Giants Odds, Game Time

• Game day: Thursday, April 16, 2026
• Game time: 12:40 p.m. ET
• Location: Cincinnati, Ohio
• Stadium: Great American Ball Park
• Favorite: Reds (-130)
• Underdog: Giants (+109)
• Over/under: 8

How to Watch Reds vs. Giants

• TV Channel: CINR and NBCS-BA
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Reds vs. Giants: Betting the Moneyline

• The Reds have been favored on the moneyline four total times this season. They've finished 3-1 in those games.
• San Francisco has been underdogs in 13 games this season and has come away with the win five times (38.5%) in those contests.
• Cincinnati has a record of 2-1 when favored by -130 or more by sportsbooks this season.
• The Giants have a mark of 2-3 in contests where sportsbooks favor them by +109 or worse on the moneyline.
• Based on this matchup's moneyline, the Reds' implied win probability is 56.5%.
• Oddsmakers have implied with the moneyline set for this matchup that the Giants have a 47.8% chance of pulling out a win.

Reds vs. Giants: Betting the Spread & Total

• The Reds have played in 18 games with over/under set, and have combined with opponents to go over the total 10 times (10-7-1).
• San Francisco's games have gone over the total in eight of its 18 chances.
• The Reds have covered 61.1% of their games this season, going 11-7-0 ATS.
• In 18 games with a line this season, the Giants have a mark of 5-13-0 against the spread.