Cubs vs. Padres Dunkel MLB Picks, Predictions and Prop Bets - April 29

The Chicago Cubs and San Diego Padres play on Wednesday at 4:10 p.m. ET at Petco Park, attempting to break a 1-1 series tie. Jameson Taillon (1-1, 4.55 ERA) gets the start for the Cubs, who are 18-12 this season and second in the NL Central. Matt Waldron (0-1, 12.46 ERA) is expected to start for the Padres, who are 19-10 and second in the NL West.

Even though the Cubs are playing on the road at the Padres, they are currently favored on the moneyline at -120, compared to the home team at +101. The game's total is set at 8.5.

Cubs vs. Padres Odds, Game Time

• Game day: Wednesday, April 29, 2026
• Game time: 4:10 p.m. ET
• Location: San Diego, California
• Stadium: Petco Park
• Favorite: Cubs (-120)
• Underdog: Padres (+101)
• Over/under: 8.5

How to Watch Cubs vs. Padres

• TV Channel: SDPA and MARQ
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Cubs vs. Padres: Betting the Moneyline

• The Cubs have won 12 of the 19 games they were favored on the moneyline this season (63.2%).
• San Diego has been pegged as an underdog in 12 games this year and has walked away with the win six times (50%) in those games.
• Chicago has a record of 10-6, a 62.5% win rate, when favored by -120 or more by oddsmakers this season.
• This year, the Padres have won four of nine games when listed as at least +101 or worse on the moneyline.
• The Cubs have an implied moneyline win probability of 54.5% in this contest.
• The Padres have an implied victory probability of 49.8% according to the moneyline set by oddsmakers for this matchup.

Cubs vs. Padres: Betting the Spread & Total

• The Cubs have played in 30 games with an over/under set, and have combined with their opponents to go over the total 19 times (19-9-2).
• So far this season, San Diego and its opponents have hit the over in 13 of its 29 games with a total.
• The Cubs have covered 50% of their games this season, going 15-15-0 against the spread.
• The Padres are 18-11-0 against the spread in their 29 games that had a posted line this season.