Cubs vs. Pirates Dunkel MLB Picks, Predictions and Prop Bets - May 25

The Chicago Cubs visit the Pittsburgh Pirates to open a four-game series at PNC Park, with first pitch at 1:35 p.m. ET on Monday. Ben Brown (1-2, 2.09 ERA) will start for the Cubs, who are 29-24 this season and third in the NL Central. Carmen Mlodzinski (4-3, 3.96 ERA) is the expected starter for the Pirates, who are 27-26 and fifth in the NL Central.

Despite being on the road the Cubs are a moderate moneyline favorite (-126) over the Pirates (+105). The over/under for the Cubs-Pirates game is set at 8.

Cubs vs. Pirates Odds, Game Time

• Game day: Monday, May 25, 2026
• Game time: 1:35 p.m. ET
• Location: Pittsburgh, Pennsylvania
• Stadium: PNC Park
• Favorite: Cubs (-126)
• Underdog: Pirates (+105)
• Over/under: 8

How to Watch Cubs vs. Pirates

• TV Channel: SportsNet PT and MARQ
• Live Stream: Fubo (Watch for free)

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Cubs vs. Pirates: Betting the Moneyline

• The Cubs have been favored on the moneyline 37 total times this season. They've finished 21-16 in those games.
• Pittsburgh has been underdogs in 22 games this season and has come away with the win eight times (36.4%) in those contests.
• Chicago has a record of 18-13 in games when bookmakers favor them by at least -126 on the moneyline.
• This season, the Pirates have come away with a win five times in 13 chances when named as an underdog of at least +105 or longer on the moneyline.
• Based on this game's moneyline, the Cubs have an implied win probability of 55.8%.
• The moneyline set for this matchup implies the Pirates have a 48.8% chance of walking away with the win.

Cubs vs. Pirates: Betting the Spread & Total

• The Cubs have combined with opponents to go over the total 29 times this season for a 29-22-2 record against the over/under.
• So far this season, Pittsburgh and its opponents have hit the over in 27 of its 53 games with a total.
• The Cubs have a 21-32-0 record against the spread this season (covering only 39.6% of the time).
• In 53 games with a line this season, the Pirates have a mark of 27-26-0 against the spread.