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Cubs vs. Astros Dunkel MLB Picks, Predictions and Prop Bets - May 24

23 May 2026 By Data Skrive

The Chicago Cubs will attempt to snap a six-game losing streak when hosting the Houston Astros at 2:20 p.m. ET on Sunday. Shota Imanaga (4-4, 3.37 ERA) will start for the Cubs, who are 29-22 this season and third in the NL Central. Peter Lambert (2-4, 3.57 ERA) is starting for the Astros, who are 21-31 and fourth in the AL West.

The Cubs (-162) are moneyline favorites at home over the Astros (+136). The contest has an over/under set at 8.

Cubs vs. Astros Odds, Game Time

  • Game day: Sunday, May 24, 2026
  • Game time: 2:20 p.m. ET
  • Location: Chicago, Illinois
  • Stadium: Wrigley Field
  • Favorite: Cubs (-162)
  • Underdog: Astros (+136)
  • Over/under: 8

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Cubs vs. Astros: Betting the Moneyline

  • The Cubs have gone 21-14 in games they were listed as the moneyline favorite (winning 60% of those games).
  • Houston has been pegged as an underdog in 36 games this year and has walked away with the win 16 times (44.4%) in those games.
  • Chicago has a record of 9-3 in games when oddsmakers favor them by at least -162 on the moneyline.
  • The Astros have a mark of 2-6 in contests where bookmakers favor them by +136 or worse on the moneyline.
  • The implied moneyline probablility for this matchup gives the Cubs a 61.8% chance to win.
  • The moneyline set for this matchup implies the Astros have a 42.4% chance of coming away with a victory in the contest.

Cubs vs. Astros: Betting the Spread & Total

  • The Cubs have played in 51 games with an over/under set, and have combined with their opponents to go over the total 28 times (28-21-2).
  • So far this season, Houston and its opponents have hit the over in 28 of its 52 games with a total.
  • The Cubs have covered 41.2% of their games this season, going 21-30-0 ATS.
  • The Astros have an against the spread mark of 21-31-0 in 52 games with a line this season.
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