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Cubs vs. Astros Dunkel MLB Picks, Predictions and Prop Bets - May 24

23 May 2026 By Data Skrive

The Chicago Cubs hope to stop their seven-game losing run against the Houston Astros, on Sunday at 2:20 p.m. ET. Shota Imanaga (4-4, 3.37 ERA) gets the start for the Cubs, who are 29-23 this season and third in the NL Central. Peter Lambert (2-4, 3.57 ERA) is starting for the Astros, who are 22-31 and fourth in the AL West.

The Cubs are moderate favorites on the moneyline (-176) at home over the Astros (+147). The game's over/under is 7.

Cubs vs. Astros Odds, Game Time

  • Game day: Sunday, May 24, 2026
  • Game time: 2:20 p.m. ET
  • Location: Chicago, Illinois
  • Stadium: Wrigley Field
  • Favorite: Cubs (-176)
  • Underdog: Astros (+147)
  • Over/under: 7

How to Watch Cubs vs. Astros

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Cubs vs. Astros: Betting the Moneyline

  • The Cubs have won 21 of the 36 games they were favored on the moneyline this season (58.3%).
  • Houston has come away with 17 wins in the 37 contests it has been listed as the underdogs in this season.
  • Chicago has a record of 5-2 in games when sportsbooks favor them by at least -176 on the moneyline.
  • The Astros have a win-loss record of 2-5 when favored by +147 or worse by oddsmakers this year.
  • Based on this game's moneyline, the Cubs have an implied win probability of 63.8%.
  • Oddsmakers have implied with the moneyline set for this matchup that the Astros have a 40.5% chance of pulling out a win.

Cubs vs. Astros: Betting the Spread & Total

  • The Cubs have played in 52 games with over/under set, and have combined with opponents to go over the total 28 times (28-22-2).
  • Games involving Houston have gone over the total set by oddsmakers in 28 of 53 chances this season.
  • The Cubs are 21-31-0 ATS this season.
  • In 53 games with a line this season, the Astros have a mark of 22-31-0 against the spread.
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