Cubs vs. Diamondbacks Dunkel MLB Picks, Predictions and Prop Bets - Aug. 25

The Chicago Cubs will look to Michael Conforto, on a two-game homer streak, versus the Arizona Diamondbacks at 9:40 p.m. ET on Tuesday, at Chase Field. Clay Holmes (5-6, 2.49 ERA) gets the start for the Cubs, who are 76-56 this season and second in the NL Central. Brandon Pfaadt (7-1, 3.39 ERA) is starting for the Diamondbacks, who are 69-63 and third in the NL West.

Sportsbooks expect a close matchup between the Cubs (-111 to win) and the Diamondbacks (-103). The game's over/under is set at 8.5.

Cubs vs. Diamondbacks Odds, Game Time

• Game day: Tuesday, August 25, 2026
• Game time: 9:40 p.m. ET
• Location: Phoenix, Arizona
• Stadium: Chase Field
• Favorite: Cubs (-111)
• Underdog: Diamondbacks (-103)
• Over/under: 8.5

How to Watch Cubs vs. Diamondbacks

• TV Channel: ARID and MARQ
• Live Stream: Fubo (Watch for free)

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Cubs vs. Diamondbacks: Betting the Moneyline

• The Cubs have compiled a 53-38 record in games they were favored on the moneyline (winning 58.2% of those games).
• Arizona has come away with 35 wins in the 76 contests it has been listed as the underdogs in this season.
• This season Chicago has won 54 of its 91 games, or 59.3%, when favored by at least -111 on the moneyline.
• This year, the Diamondbacks have won 29 of 64 games when listed as at least -103 or worse on the moneyline.
• The Cubs have a 52.6% chance to win this matchup based on the moneyline's implied probability.
• Oddsmakers have implied with the moneyline set for this matchup that the Diamondbacks have a 50.7% chance of pulling out a win.

Cubs vs. Diamondbacks: Betting the Spread & Total

• The Cubs have had an over/under set by bookmakers 132 times, and have combined with opponents to go over the total in 71 of those games (71-58-3).
• So far this season, Arizona and its opponents have hit the over in 58 of its 132 games with a total.
• The Cubs have put together a 63-69-0 record ATS this season (covering 47.7% of the time).
• The Diamondbacks are 72-60-0 against the spread in their 132 games that had a posted line this season.