Panthers vs. Eagles Week 6 Dunkel NFL Picks, Predictions and Odds

The Carolina Panthers (2-2) are slim favorites (-1.5) over the Philadelphia Eagles (2-3). The Eagles have lost three games in a row. The over/under for this one is set at 39.5 points.

The Panthers own the 26th-ranked defense this season (27.3 points allowed per game), and they've been better on the other side of the ball, ranking fourth-best with 30.3 points per game. The Eagles rank fourth-worst in points per game (18.4), but they've been better defensively, ranking 14th in the NFL with 22.4 points ceded per contest.

Panthers vs. Eagles Odds and Game Time

• Date: Sunday, October 18, 2026
• Time: 1 p.m. ET
• City: Philadelphia, Pennsylvania
• Venue: Lincoln Financial Field
• Total: 39.5 points
• Spread: Panthers -1.5
• Moneyline: Panthers (-115), Eagles (-105)

How to watch Panthers vs. Eagles

• TV Channel: CBS

Betting the Over/Under: Panthers vs. Eagles

• In two games this season, the Panthers and their opponents have combined to put up more than 39.5 points.
• Carolina games have hit the over twice this season.
• The Eagles have played three games this season that have had more than 39.5 combined points scored.
• So far this year, three of Philadelphia's five games with a set number have hit the over.
• The two teams combine to score 48.7 points per game, 9.2 more points than this matchup's total.
• These two teams surrender a combined 49.7 points per game, 10.2 more points than this matchup's total.

Betting the Spread: Panthers vs. Eagles

• Carolina has a record of 2-2-0 against the spread this season.
• Carolina has been favored by 1.5 points or more two times this season, and covered the spread in one of those games.
• The Eagles have a record of 2-3-0 against the spread this season.
• Philadelphia has been an underdog by 1.5 points or more two times this season, and covered the spread both times.

Betting the Moneyline: Panthers vs. Eagles

• Carolina has been listed as the moneyline favorite just two other times so far this season, and they split the two games.
• The Eagles have lost both games they've played as underdogs this season.
• Carolina has played as a moneyline favorite of -115 or shorter in just two games this season, and it split 1-1.
• This season, Philadelphia has been at least a -105 underdog on the moneyline two times, losing each of those contests.
• The implied moneyline probability for this matchup gives the Panthers a 53.5% chance to win.

Dunkel Prediction for Panthers vs. Eagles

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