Bills vs. Raiders Week 6 Dunkel NFL Picks, Predictions and Odds

The Buffalo Bills (4-1) are considered favorites (-4.5) according to the bookmakers ahead of their game against the Las Vegas Raiders (3-2) on October 18, 2026, starting at 4:25 p.m. ET, airing on CBS. An over/under of 53.5 points has been set for the matchup.

While the Bills rank fifth-worst in the NFL in scoring defense with 28.2 points allowed per game, it's been a different story on offense, as they rank best in the NFL (32.8 points per game). In terms of points scored the Raiders rank ninth in the NFL (26.4 points per game), and they are 22nd on the other side of the ball (25.8 points allowed per contest).

Bills vs. Raiders Odds and Game Time

• Date: Sunday, October 18, 2026
• Time: 4:25 p.m. ET
• City: Paradise, Nevada
• Venue: Allegiant Stadium
• Total: 53.5 points
• Spread: Bills -4.5
• Moneyline: Bills (-250), Raiders (+205)

How to watch Bills vs. Raiders

• TV Channel: CBS

Betting the Over/Under: Bills vs. Raiders

• Bills games this season have featured more combined points than this contest's total of 53.5 points four times.
• In Buffalo's five games this season, the combined scoring has gone over the point total four times.
• The Raiders and their opponents have combined to score more than 53.5 points in three of five games this season.
• In Las Vegas' five contests this year, the combined scoring has gone over the point total three times.
• These two teams score a combined 59.2 points per game, 5.7 more points than this matchup's point total.
• These teams give up 54 points per game combined, 0.5 more points than the over/under for this contest.

Betting the Spread: Bills vs. Raiders

• Buffalo has won four games against the spread this season, while failing to cover once.
• Buffalo has been favored by 4.5 points or more three times this season, and covered the spread in two of those matchups.
• The Raiders have put together a 4-1-0 record against the spread this year.
• Las Vegas has been an underdog by 4.5 points or more two times this year, and covered the spread both times.

Betting the Moneyline: Bills vs. Raiders

• Buffalo is 3-1 in games they were listed as the moneyline favorite (winning 75% of those games).
• The Raiders have won two of the four games they've played as underdogs this season.
• Buffalo has played as a moneyline favorite of -250 or shorter in just two games this season, and it split 1-1.
• Las Vegas has played as an underdog of +205 or more once this season and won that game.
• The implied moneyline probability for this matchup gives the Bills a 71.4% chance to win.

Dunkel Prediction for Bills vs. Raiders

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