Red Sox vs. Giants Dunkel MLB Picks, Predictions and Prop Bets - Aug. 21

The Boston Red Sox will look to Mickey Gasper, riding a three-game homer streak, versus the San Francisco Giants at 7:10 p.m. ET on Friday, at Fenway Park. Sonny Gray (15-3, 2.65 ERA) gets the start for the Red Sox, who are 68-59 this season and third in the AL East. Logan Webb (8-7, 3.50 ERA) is the expected starter for the Giants, who are 52-75 and fourth in the NL West.

The Red Sox (-177) are moneyline favorites at home over the Giants (+155). The game has an over/under of 7.5 runs.

Red Sox vs. Giants Odds, Game Time

• Game day: Friday, August 21, 2026
• Game time: 7:10 p.m. ET
• Location: Boston, Massachusetts
• Stadium: Fenway Park
• Favorite: Red Sox (-177)
• Underdog: Giants (+155)
• Over/under: 7.5

How to Watch Red Sox vs. Giants

• TV Channel: NESN and NBCS-BA
• Live Stream: Fubo (Watch for free)

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Red Sox vs. Giants: Betting the Moneyline

• The Red Sox have won 46 of the 87 games they were the moneyline favorite this season (52.9%).
• San Francisco has been underdogs in 80 games this season and has come away with the win 29 times (36.2%) in those contests.
• Boston has entered nine games this season favored by -177 or more and is 6-3 in those contests.
• This year, the Giants have won six of 12 games when listed as at least +155 or worse on the moneyline.
• Based on this matchup's moneyline, the Red Sox's implied win probability is 63.9%.
• The Giants have an implied victory probability of 39.2% according to the moneyline set for this matchup.

Red Sox vs. Giants: Betting the Spread & Total

• The Red Sox have played in 127 games with a set over/under, and have combined with their opponents to go over the total 58 times (58-64-5).
• San Francisco and its opponents have hit the over in 58 of its 126 games with a total this season.
• The Red Sox are 63-64-0 against the spread this season.
• In 126 games with a line this season, the Giants have a mark of 60-66-0 against the spread.