Orioles vs. Tigers Dunkel MLB Picks, Predictions and Prop Bets - May 22

The Detroit Tigers hope to stop their six-game losing run against the Baltimore Orioles, at 7:15 p.m. ET on Friday. Chris Bassitt (3-3, 5.44 ERA) gets the start for the Orioles, who are 21-29 this season and fifth in the AL East. Jack Flaherty (0-5, 5.77 ERA) is starting for the Tigers, who are 20-31 and fifth in the AL Central.

With the Tigers (+118) visiting, the Orioles (-141) are a solid favorite on the moneyline. The contest has a total set at 8.5.

Orioles vs. Tigers Odds, Game Time

• Game day: Friday, May 22, 2026
• Game time: 7:15 p.m. ET
• Location: Baltimore, Maryland
• Stadium: Oriole Park at Camden Yards
• Favorite: Orioles (-141)
• Underdog: Tigers (+118)
• Over/under: 8.5

How to Watch Orioles vs. Tigers

• TV Channel: Apple TV+
• Live Stream: Fubo (Watch for free)

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Orioles vs. Tigers: Betting the Moneyline

• The Orioles have been favored on the moneyline 26 total times this season. They've gone 13-13 in those games.
• Detroit has been victorious in seven, or 33.3%, of the 21 contests it has been chosen as underdogs in this season.
• Baltimore has a record of 4-2 in games when sportsbooks favor them by at least -141 on the moneyline.
• This season, the Tigers have come away with a win one times in five chances when named as an underdog of at least +118 or worse on the moneyline.
• Based on this game's moneyline, the Orioles' implied win probability is 58.5%.
• The moneyline set for this matchup implies the Tigers have a 45.9% chance of walking away with the win.

Orioles vs. Tigers: Betting the Spread & Total

• The Orioles have had an over/under set by oddsmakers 50 times, and have combined with opponents to go over the total in 28 of those games (28-21-1).
• Detroit and its opponents have hit the over in 22 of its 51 games with a total this season.
• The Orioles have collected a 21-29-0 record against the spread this season.
• The Tigers have posted a record of 25-26-0 against the spread this season.