Diamondbacks vs. Rockies Dunkel MLB Picks, Predictions and Prop Bets - May 21

The Arizona Diamondbacks host the Colorado Rockies to start a four-game series at Chase Field, with first pitch at 9:40 p.m. ET on Thursday. Eduardo Rodriguez (4-1, 2.53 ERA) gets the start for the Diamondbacks, who are 25-23 this season and third in the NL West. Zach Agnos (0-0, 5.59 ERA) is the expected starter for the Rockies, who are 19-31 and fifth in the NL West.

The bookmakers have spoken, making the Diamondbacks (-208) a moderate moneyline favorite to defeat the Rockies (+172) at home. The over/under for the Diamondbacks-Rockies game is set at 9.

Diamondbacks vs. Rockies Odds, Game Time

• Game day: Thursday, May 21, 2026
• Game time: 9:40 p.m. ET
• Location: Phoenix, Arizona
• Stadium: Chase Field
• Favorite: Diamondbacks (-208)
• Underdog: Rockies (+172)
• Over/under: 9

How to Watch Diamondbacks vs. Rockies

• TV Channel: ARID and COLR
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Diamondbacks vs. Rockies: Betting the Moneyline

• The Diamondbacks have a 13-6 record in games they were listed as the moneyline favorite (winning 68.4% of those games).
• Colorado has been underdogs in 49 games this season and has come away with the win 19 times (38.8%) in those contests.
• Arizona has not entered a game this season as bigger favorites on the moneyline than the -208 odds on them winning this game.
• This season, the Rockies have come away with a win six times in 14 chances when named as an underdog of at least +172 or worse on the moneyline.
• The Diamondbacks have an implied moneyline win probability of 67.5% in this game.
• The Rockies have an implied victory probability of 36.8% according to the moneyline set by sportsbooks for this matchup.

Diamondbacks vs. Rockies: Betting the Spread & Total

• The Diamondbacks have played in 48 games with an over/under set, and have combined with their opponents to go over the total 25 times (25-21-2).
• So far this season, Colorado and its opponents have hit the over in 23 of its 50 games with a total.
• The Diamondbacks have collected a 30-18-0 record ATS this season (covering 62.5% of the time).
• The Rockies are 26-24-0 against the spread in their 50 games that had a posted line this season.