Diamondbacks vs. Reds Dunkel MLB Picks, Predictions and Prop Bets - Aug. 21

The Arizona Diamondbacks are looking for Gabriel Moreno to prolong a 13-game hitting streak versus the Cincinnati Reds on Friday at 9:40 p.m. ET, at Chase Field. Eduardo Rodriguez (12-4, 2.71 ERA) will start for the Diamondbacks, who are 67-61 this season and third in the NL West. Nick Lodolo (3-2, 4.52 ERA) is expected to start for the Reds, who are 61-67 and fifth in the NL Central.

At home, the Diamondbacks are favored to win on the moneyline (-145) over the Reds (+128). The game has an over/under set at 8.5 runs.

Diamondbacks vs. Reds Odds, Game Time

• Game day: Friday, August 21, 2026
• Game time: 9:40 p.m. ET
• Location: Phoenix, Arizona
• Stadium: Chase Field
• Favorite: Diamondbacks (-145)
• Underdog: Reds (+128)
• Over/under: 8.5

How to Watch Diamondbacks vs. Reds

• TV Channel: ARID and CINR
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Diamondbacks vs. Reds: Betting the Moneyline

• The Diamondbacks have a 31-21 record in games they were favored on the moneyline (winning 59.6% of those games).
• Cincinnati has been pegged as an underdog in 87 games this year and has walked away with the win 38 times (43.7%) in those games.
• This season Arizona has won nine of its 17 games, or 52.9%, when favored by at least -145 on the moneyline.
• The Reds have a win-loss record of 7-13 when favored by +128 or worse by oddsmakers this year.
• The Diamondbacks have a 59.2% chance to win this contest based on the moneyline's implied probability.
• The Reds have an implied victory probability of 43.9% according to the moneyline set by oddsmakers for this matchup.

Diamondbacks vs. Reds: Betting the Spread & Total

• The Diamondbacks have played in 128 games with an over/under set, and have combined with their opponents to go over the total 56 times (56-67-5).
• Cincinnati and its opponents have gone over the total this season in 67 of its 128 opportunities.
• The Diamondbacks have put together a 70-58-0 record against the spread this season (covering 54.7% of the time).
• The Reds are 67-61-0 against the spread in their 128 games that had a posted line this season.