Rays vs. Reds Dunkel MLB Picks, Predictions and Prop Bets - April 22

The Cincinnati Reds take on the Tampa Bay Rays, a game after Elly De La Cruz went deep twice in a 12-6 victory over the Rays, at 1:10 p.m. ET on Wednesday. Nick Martinez (0-1, 2.45 ERA) gets the start for the Rays, who are 12-11 this season and second in the AL East. Brandon Williamson (2-1, 4.35 ERA) is the expected starter for the Reds, who are 16-8 and first in the NL Central.

The Rays are moderate favorites on the moneyline (-139) at home over the Reds (+117). The game's total is set at 8.5.

Rays vs. Reds Odds, Game Time

• Game day: Wednesday, April 22, 2026
• Game time: 1:10 p.m. ET
• Location: St. Petersburg, Florida
• Stadium: Tropicana Field
• Favorite: Rays (-139)
• Underdog: Reds (+117)
• Over/under: 8.5

How to Watch Rays vs. Reds

• TV Channel: RAYS and CINR
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Rays vs. Reds: Betting the Moneyline

• The Rays have gone 6-5 in games they were listed as the moneyline favorite (winning 54.5% of those games).
• Cincinnati has been victorious in 12, or 66.7%, of the 18 contests it has been chosen as underdogs in this season.
• Tampa Bay has not entered a game this season with shorter moneyline odds than -139.
• This year, the Reds have won four of six games when listed as at least +117 or worse on the moneyline.
• The implied moneyline probablility for this matchup gives the Rays a 58.2% chance to win.
• The moneyline set for this matchup implies the Reds have a 46.1% chance of coming away with a victory in the contest.

Rays vs. Reds: Betting the Spread & Total

• The Rays have combined with opponents to hit the over on the total 15 times this season for a 15-6-2 record against the over/under.
• So far this season, Cincinnati and its opponents have hit the over in 13 of its 24 games with a total.
• The Rays have covered 52.2% of their games this season, going 12-11-0 against the spread.
• In 24 games with a line this season, the Reds have a mark of 16-8-0 against the spread.