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Cardinals vs. Pirates Dunkel MLB Picks, Predictions and Prop Bets - May 19

19 May 2026 By Data Skrive

The Pittsburgh Pirates hope to stop their three-game losing run against the St. Louis Cardinals, at 7:45 p.m. ET on Tuesday. Matthew Liberatore (2-2, 4.40 ERA) will start for the Cardinals, who are 27-19 this season and third in the NL Central. Mitch Keller (4-2, 3.59 ERA) is expected to start for the Pirates, who are 24-23 and fourth in the NL Central.

Bookmakers expect a close matchup between the Cardinals (-118 to win) and the Pirates (-101). The game's over/under is set at 8.

Cardinals vs. Pirates Odds, Game Time

  • Game day: Tuesday, May 19, 2026
  • Game time: 7:45 p.m. ET
  • Location: St. Louis, Missouri
  • Stadium: Busch Stadium
  • Favorite: Cardinals (-118)
  • Underdog: Pirates (-101)
  • Over/under: 8

How to Watch Cardinals vs. Pirates

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Cardinals vs. Pirates: Betting the Moneyline

  • The Cardinals have put together a 3-3 record in games they were favored on the moneyline (winning 50% of those games).
  • Pittsburgh has been underdogs in 18 games this season and has come away with the win six times (33.3%) in those contests.
  • St. Louis has played as favorites of -118 or more twice this season and split those games.
  • This year, the Pirates have won five of 15 games when listed as at least -101 or worse on the moneyline.
  • The Cardinals have an implied moneyline win probability of 54.1% in this game.
  • The Pirates have an implied victory probability of 50.2% according to the moneyline set by oddsmakers for this matchup.

Cardinals vs. Pirates: Betting the Spread & Total

  • The Cardinals have combined with opponents to hit the over on the total 18 times this season for an 18-23-5 record against the over/under.
  • Pittsburgh's games have gone over the total in 25 of its 47 chances.
  • The Cardinals have covered 63% of their games this season, going 29-17-0 ATS.
  • The Pirates have posted a record of 24-23-0 against the spread this season.
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