Cardinals vs. Reds Dunkel MLB Picks, Predictions and Prop Bets - June 5

The St. Louis Cardinals and Cincinnati Reds square off in the first of a three-game series on Friday at Busch Stadium, at 8:15 p.m. ET. Kyle Leahy (5-3, 4.25 ERA) gets the start for the Cardinals, who are 32-28 this season and third in the NL Central. Brady Singer (2-5, 6.18 ERA) is the expected starter for the Reds, who are 31-30 and fifth in the NL Central.

The Cardinals (-142) are moneyline favorites at home over the Reds (+119). The game's total is 9.

Cardinals vs. Reds Odds, Game Time

• Game day: Friday, June 5, 2026
• Game time: 8:15 p.m. ET
• Location: St. Louis, Missouri
• Stadium: Busch Stadium
• Favorite: Cardinals (-142)
• Underdog: Reds (+119)
• Over/under: 9

How to Watch Cardinals vs. Reds

• TV Channel: CARD and CINR
• Live Stream: Fubo (Watch Now!)

Bet now on FanDuel Sportsbook!

Cardinals vs. Reds: Betting the Moneyline

• The Cardinals have a 6-4 record in games they were listed as the moneyline favorite (winning 60% of those games).
• Cincinnati has been victorious in 19, or 48.7%, of the 39 contests it has been chosen as underdogs in this season.
• St. Louis has not entered a game this season as bigger favorites on the moneyline than the -142 odds on them winning this game.
• This year, the Reds have won four of 12 games when listed as at least +119 or worse on the moneyline.
• Based on this matchup's moneyline, the Cardinals have an implied win probability of 58.7%.
• The moneyline set for this matchup implies the Reds have a 45.7% chance of coming away with a victory in the contest.

Cardinals vs. Reds: Betting the Spread & Total

• The Cardinals have combined with opponents to go over the total 23 times this season for a 23-31-6 record against the over/under.
• Cincinnati's games have gone over the total in 37 of its 61 chances.
• The Cardinals have a 36-24-0 record against the spread this season.
• The Reds are 34-27-0 against the spread in their 61 games with a line set by sportsbooks this season.