Giants vs. Royals Dunkel MLB Picks, Predictions and Prop Bets - July 22

The Kansas City Royals will attempt to sweep the San Francisco Giants at Kauffman Stadium on Wednesday, at 2:10 p.m. ET. Landen Roupp (7-8, 3.98 ERA) will start for the Giants, who are 42-59 this season and fourth in the NL West. Seth Lugo (3-6, 4.39 ERA) is the expected starter for the Royals, who are 42-60 and fifth in the AL Central.

Despite being the away team the Giants are a moderate moneyline favorite (-130) over the Royals (+107). The game's total is set at 8.5.

Giants vs. Royals Odds, Game Time

• Game day: Wednesday, July 22, 2026
• Game time: 2:10 p.m. ET
• Location: Kansas City, Missouri
• Stadium: Kauffman Stadium
• Favorite: Giants (-130)
• Underdog: Royals (+107)
• Over/under: 8.5

How to Watch Giants vs. Royals

• TV Channel: ROYL and NBCS-BA
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Giants vs. Royals: Betting the Moneyline

• The Giants have gone 18-20 in games they were listed as the moneyline favorite (winning 47.4% of those games).
• Kansas City has won in 25, or 37.9%, of the 66 contests it has been named as odds-on underdogs in this year.
• This season San Francisco has won nine of its 18 games, or 50%, when favored by at least -130 on the moneyline.
• This season, the Royals have been victorious 13 times in 37 chances when named as an underdog of at least +107 or worse on the moneyline.
• The Giants have an implied moneyline win probability of 56.5% in this contest.
• The Royals have an implied victory probability of 48.3% according to the moneyline set for this matchup.

Giants vs. Royals: Betting the Spread & Total

• The Giants have played in 100 games with a set over/under, and have combined with their opponents to go over the total 46 times (46-46-8).
• Games involving Kansas City have gone over the total set by oddsmakers in 49 of 102 chances this season.
• The Giants have a 46-54-0 record against the spread this season.
• The Royals are 44-58-0 against the spread in their 102 games with a line set by sportsbooks this season.