49ers vs. Falcons Week 7 Dunkel NFL Picks, Predictions and Odds

The San Francisco 49ers (6-0) will be trying to continue a six-game winning run against the Atlanta Falcons (2-4). The 49ers are the favorites, expected to win by at least a field goal but less than a touchdown (currently -3). The predicted point total for the game is 49.5.

The 49ers rank ninth in total offense this season (366.7 yards per game), but they've been playing really well on the other side of the ball, ranking fifth-best in the NFL with 366.7 yards allowed per game. The Falcons rank 12th with 344.3 total yards per contest on offense, and they rank 18th with 335.2 total yards given up per game on the defensive side of the ball.

49ers vs. Falcons Odds and Game Time

• Date: Sunday, October 25, 2026
• Time: 1 p.m. ET
• City: Atlanta, Georgia
• Venue: Mercedes-Benz Stadium
• Total: 49.5 points
• Spread: 49ers -3
• Moneyline: 49ers (-170), Falcons (+142)

How to watch 49ers vs. Falcons

• TV Channel: FOX

Betting the Over/Under: 49ers vs. Falcons

• 49ers games have had a combined total of more than 49.5 points two times this season (over six outings).
• San Francisco and its opponent have combined to hit the over three out of six times this season.
• The Falcons have played three games this season that finished with a combined score over 49.5 points.
• So far this season, four of Atlanta's six games with a set number have hit the over.
• These two teams average 53.2 points per game between them, 3.7 more than this game's point total.
• These teams allow a combined 43.8 points per game, 5.7 fewer points than this matchup's over/under.

Betting the Spread: 49ers vs. Falcons

• San Francisco has compiled a 4-2-0 record against the spread this season.
• San Francisco has covered the spread twice when favored by 3 points or more this season (in four opportunities).
• The Falcons have covered twice in six chances against the spread this season.
• Atlanta has covered the spread once this year (1-1 ATS) when playing as at least 3-point underdogs.
• The Falcons are winless against the spread, and 0-3 overall, at home this season.

Betting the Moneyline: 49ers vs. Falcons

• San Francisco has been the moneyline favorite a total of four times this season, and they've won all of those games.
• The Falcons have won two of the five games they've played as underdogs this season.
• San Francisco has played three times as a moneyline favorite with odds of -170 or shorter, and won in each game.
• Atlanta has entered two games this season as the underdog by +142 or more and is 1-1 in those contests.
• The 49ers have a 63.0% chance to win this game based on the moneyline's implied probability.

Dunkel Prediction for 49ers vs. Falcons

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