Padres vs. Reds Dunkel MLB Picks, Predictions and Prop Bets - Sept. 2
02 September 2026

The San Diego Padres visit the Cincinnati Reds at 12:40 p.m. ET on Wednesday, with both teams hoping to win the series. Casey Mize (5-8, 3.45 ERA) will start for the Padres, who are 73-66 this season and second in the NL West. Brandon Williamson (2-3, 6.11 ERA) is the expected starter for the Reds, who are 66-73 and fifth in the NL Central.
Despite being the away team the Padres are a moderate moneyline favorite (-164) over the Reds (+134). The total for this contest is set at 9.5.
Padres vs. Reds Odds, Game Time
- Game day: Wednesday, September 2, 2026
- Game time: 12:40 p.m. ET
- Location: Cincinnati, Ohio
- Stadium: Great American Ball Park
- Favorite: Padres (-164)
- Underdog: Reds (+134)
- Over/under: 9.5
How to Watch Padres vs. Reds
- TV Channel: CINR and SDPA
- Live Stream: Fubo (Watch for free)
Bet now on FanDuel Sportsbook!
Padres vs. Reds: Betting the Moneyline
- The Padres have won 57.1% of the games this season when they were favored on the moneyline (36-27).
- Cincinnati has been pegged as an underdog in 97 games this year and has walked away with the win 43 times (44.3%) in those games.
- San Diego has a record of 8-4, a 66.7% win rate, when favored by -164 or more by bookmakers this season.
- The Reds have a mark of 10-11 in contests where bookmakers favor them by +134 or worse on the moneyline.
- The implied moneyline probablility in this matchup gives the Padres a 62.1% chance to win.
- The moneyline set for this matchup implies the Reds have a 42.7% chance of walking away with the win.
Padres vs. Reds: Betting the Spread & Total
- The Padres have had an over/under set by bookmakers 139 times, and have combined with opponents to go over the total in 61 of those games (61-74-4).
- Games involving Cincinnati have gone over the total set by bookmakers in 73 of 139 chances this season.
- The Padres have a 79-60-0 record against the spread this season (covering 56.8% of the time).
- The Reds are 71-68-0 against the spread in their 139 games with a line set by sportsbooks this season.
