Sabres vs. Flyers NHL Predictions, Picks and Odds - Oct. 21

The Buffalo Sabres and Philadelphia Flyers -- the former coming off a defeat, the latter a win -- will face each other on Wednesday at 7:30 p.m. ET, at KeyBank Center in Buffalo. The Flyers are underdogs away from home, at +160, and the Sabres are -192.

Buffalo fell in a 4-3 overtime loss on the road its last time out on Oct. 17 against the Montreal Canadiens. The Sabres got one point apiece out of eight players, including Mattias Samuelsson (one assist) and Zachary Benson (one assist).

Philadelphia won its most recent game 3-2 at home over the Colorado Avalanche on Oct. 19. Joseph Woll earned the win in goal for the Flyers while making 24 saves and allowing two goals in that outing.

Ahead of watching this matchup, here's our prediction for which club will take home the victory in Wednesday's hockey action.

Sabres vs. Flyers Predictions & Pick

For predictions on the upcoming game between the Buffalo Sabres and Philadelphia Flyers, computer-derived moneyline, over/under, and score predictions are below, based on data from Dunkel Index.

• Prediction: Flyers 2 - Sabres 1
• Pick OU: Under 6.5 (Dunkel projecting 3 goals)
  

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Sabres vs. Flyers Moneylines

Take a look below at the most recent moneylines for the Sabres-Flyers game.

• Favorite: Sabres (-192)
• Underdog: Flyers (+160)

Sabres Betting Insights

• The Sabres are 2-1 when listed as a moneyline favorite this season.
• Buffalo has had moneyline odds of -192 or shorter once this season, and won.
• The Sabres' implied moneyline win probability is 65.8% in this game.
• Buffalo and its opponent have combined to score more than 6.5 goals in six of nine games this season.

Flyers Betting Insights

• The Flyers have been an underdog in nine games this season, and won two (22.2%).
• This season Philadelphia has won one of its three games when it's the underdog by at least +160 on the moneyline.
• The oddsmakers' moneyline implies a 38.5% chance of victory for the Flyers.
• Philadelphia and its opponent have combined for more than 6.5 goals just once this season.

Sabres Key Stats

• Buffalo's 27 total goals (3.0 per game) rank 19th in the league.
• Defensively, the Sabres are allowing 33 total goals (3.7 per game) to rank 23rd in league play.
• Its -6 goal differential ranks 24th in the league.
• The three power-play goals the Sabres have scored this season (to rank 30th in the NHL) have come on 33 power-play chances.
• Buffalo's 9.09% power-play conversion rate ranks 31st in the league.
• The one shorthanded goal the Sabres have scored this season rank ninth among NHL teams.
• Buffalo has the league's 30th-ranked penalty-kill percentage (64.52%).
• Buffalo wins 46.2% of its faceoffs (27th in NHL).
• The Sabres shoot 11.2% as a team (18th in the league).

Flyers Key Stats

• With 17 goals (1.6 per game), Philadelphia has the league's 30th-ranked offense.
• The Flyers have given up 35 total goals this season (3.2 per game), 28th in the NHL.
• it has the 30th-ranked goal differential in the league at -18.
• The Flyers have four power-play goals (on 31 chances), 24th in the NHL.
• Philadelphia scores on 12.90% of its power plays, No. 27 in the NHL.
• Philadelphia's has the eighth-best penalty-kill percentage (84.62%).
• At 51.5%, Philadelphia has the NHL's 12th-ranked faceoff win rate.
• With a shooting percentage of 7.2%, the Flyers are 31st in the league.