76ers vs. Cavaliers Dunkel NBA Picks, Predictions and Odds - Jan. 16

Donovan Mitchell and the Cleveland Cavaliers (23-19) battle Tyrese Maxey and the Philadelphia 76ers (22-17) on January 16, 2026 at Xfinity Mobile Arena.

The 76ers take on the Cavaliers in a game that Philadelphia is currently a modest favorite by 2.5 points. A 232.5-point over/under is set for the game.

76ers vs. Cavaliers Odds and Game Time

• Game day: Friday, January 16, 2026
• Game time: 7 p.m. ET
• Location: Philadelphia, Pennsylvania
• Arena: Xfinity Mobile Arena
• Total: 232.5 points
• Spread: 76ers -2.5
• Moneyline: 76ers (-142), Cavaliers (+120)

How to watch 76ers vs. Cavaliers

• TV Channel: ESPN
• Live Stream: Fubo

Betting the Over/Under: 76ers vs. Cavaliers

• The 76ers and their opponents have gone over 232.5 combined points in 20 of 39 games this season.
• The Cavaliers have played 22 games this season that ended with a combined score over 232.5 points.
• These two teams rack up a combined 236.9 points per game, 4.4 more points than this matchup's over/under.
• These two teams allow 233.1 points per game combined, 0.6 more points than the over/under for this matchup.

Betting the Spread: 76ers vs. Cavaliers

• Philadelphia has won 21 games against the spread this season, while failing to cover or pushing 18 times.
• When playing as at least 2.5-point favorites this season, the 76ers have an ATS record of 10-5.
• The Cavaliers have covered 15 times in 42 chances against the spread this year.
• Cleveland has been an underdog by 2.5 points or more five times this season, and covered the spread in three of those matchups.
• At home this season, the 76ers are 8-11-1 against the spread and 10-10 overall.
• This year, as a 2.5-point favorite or more at home, Philadelphia is 4-5 ATS.
• Away from home, the Cavaliers are 9-9 overall and 7-11 against the spread.
• Away from home, Cleveland has two wins ATS (2-7) as 2.5-point underdogs or more.

Betting the Moneyline: 76ers vs. Cavaliers

• The 76ers have gone 17-8 in games they were listed as the moneyline favorite (winning 68% of those games).
• The Cavaliers have entered the game as underdogs eight times this season and won three of those games.
• Philadelphia has a record of 12-2 when it has played as a moneyline favorite with odds of -142 or shorter (winning 85.7%).
• Cleveland has a record of 2-2 when it is set as the underdog by +120 or more by bookmakers this season.
• Based on this contest's moneyline, the 76ers have an implied win probability of 58.7%.

Dunkel Index Prediction for 76ers vs. Cavaliers

• Pick ATS: Cavaliers (+ 2.5)
• Pick OU: Under (232.5)
  
• Prediction: Cavaliers 115 - 76ers 111
• Check out the rest of our Dunkel Index NBA Picks!