NFL Week 4 Betting Preview
29 September 2022

The first three weeks of the NFL season have been wildly unpredictable, and it has led to some great drama. There are some huge games on the schedule in Week 4, and it could provide even more excitement.
Here is a look at all of the Week 4 matchups, with a betting pick for each game.
Miami Dolphins at Cincinnati Bengals (-3.5)
Time: 8:15 pm ET
Dunkel Ratings: Miami 141.033; Cincinnati 134.109
Dunkel Line & Total: Miami by 7; 51
Vegas Line & Total: Cincinnati by 3 ½; 47
Dunkel Pick: Miami (+3 ½); Over
The 3-0 Dolphins take on the 1-2 Bengals on Thursday Night Football. Everyone is waiting around for the Bengals to resemble the team from a season ago, but it just might not happen. Miami is on a roll, and they pick up another impressive win in this one.
Minnesota Vikings -2.5 at New Orleans Saints
Time: 9:30 am ET
Dunkel Ratings: Minnesota 129.410; New Orleans 128.633
Dunkel Line & Total: Minnesota by 1; 47
Vegas Line & Total: Minnesota by 2 ½; 44
Dunkel Pick: New Orleans (+2 ½); Over
The Minnesota Vikings look to move to 3-1 on the year when they face a tough New Orleans Saints team that is struggling. This game has all the makings of a great battle, and the Vikings will win the game but won’t be able to cover the 2.5-point spread.
Cleveland Browns -1.5 at Atlanta Falcons
Time: 1:00 pm ET
Dunkel Ratings: Cleveland 134.675; Atlanta 124.194
Dunkel Line & Total: Cleveland by 10 ½; 46
Vegas Line & Total: Cleveland by 1 ½; 50
Dunkel Pick: Cleveland (-1 ½); Under
The Browns have been surviving without quarterback Deshaun Watson, and they have another great opportunity in Week 4. Atlanta is a team that can get some things done, but that won’t be the case in this one. Cleveland will roll to a double-digit victory in this game.
Washington Commanders at Dallas Cowboys (-3.0)
Time: 1:00 pm ET
Dunkel Ratings: Washington 130.204; Dallas 128.602
Dunkel Line & Total: Washington by 2; 38
Vegas Line & Total: Dallas by 3; 42
Dunkel Pick: Washington (+3); Under
NFC East rivals meet in Dallas as the Cowboys look to move to 3-1 against the Commanders. Washington has not been good to start the year, but they have a defense that will present a challenge in this one. This will be a slight upset as Washington wins in Dallas.
Seattle Seahawks at Detroit Lions (-6.0)
Time: 1:00 pm ET
Dunkel Ratings: Seattle 121.858; Detroit 134.667
Dunkel Line & Total: Detroit by 13; 47
Vegas Line & Total: Detroit by 6; 50
Dunkel Pick: Detroit (-6); Under
The Detroit Lions are playing well, but they just haven’t been able to finish games. That won’t be a problem against a Seattle Seahawks team that struggles to score points. Take the Lions -6.0, as this is a blowout win in Week 4.
Tennessee Titans at Indianapolis Colts (-3.0)
Time: 1:00 pm ET
Dunkel Ratings: Tennessee 122.853; Indianapolis 132.780
Dunkel Line & Total: Indianapolis by 10; 46
Vegas Line & Total: Indianapolis by 3; 42
Dunkel Pick: Indianapolis (-3); Over
The AFC South has been a mess to begin the year, and the two top teams are set to meet up in Week 4. This game always seems to deliver a great matchup, but it’s not going to be the case in this one. Bet on the Colts -3.0 as they roll to a big win.
Chicago Bears at New York Giants (-3.0)
Time: 1:00 pm ET
Dunkel Ratings: Chicago 127.868; NY Giants 124.520
Dunkel Line & Total: Chicago by 3 ½; 35
Vegas Line & Total: NY Giants by 3; 39
Dunkel Pick: Chicago (+3); Under
The Bears and Giants are both 2-1 to begin the year, and that has been a pleasant surprise. That creates a big matchup in Week 4, and it’s one that should favor the Chicago Bears. Look for Chicago to take control of this game on defense as they pick up a big win.
Jacksonville Jaguars at Philadelphia Eagles (-6.5)
Time: 1:00 pm ET
Dunkel Ratings: Jacksonville 131.942; Philadelphia 141.737
Dunkel Line & Total: Philadelphia by 10; 42
Vegas Line & Total: Philadelphia by 6 ½; 48
Dunkel Pick: Philadelphia (-6 ½); Under
The Jaguars are a surprise team at 2-1, but they are going to meet their match in this one. Philadelphia is a perfect 3-0 on the year, and the Eagles have been dominant through four weeks. Take the Eagles -6.5, as this game should get out of hand.
New York Jets a Pittsburgh Steelers (-3.5)
Time: 1:00 pm ET
Dunkel Ratings: NY Jets 121.858; Pittsburgh 128.427
Dunkel Line & Total: Pittsburgh by 6 ½; 36
Vegas Line & Total: Pittsburgh by 3 ½; 42
Dunkel Pick: Pittsburgh (-3 ½); Under
The Jets and Steelers are both 1-2 on the year through three weeks, and each team has struggled at times. This game should be competitive throughout, but the Steelers will ultimately win the game and cover the 3.5 points.
Buffalo Bills -3.5 at Baltimore Ravens
Time: 1:00 pm ET
Dunkel Ratings: Buffalo 139.034; Baltimore 141.657
Dunkel Line & Total: Baltimore by 2 ½; 58
Vegas Line & Total: Buffalo by 3 ½; 52
Dunkel Pick: Baltimore (+3 ½); Over
The Bills are surprising road favorites in Baltimore as they face a Ravens team that is tough as well. This game could turn into a shootout, and it will be one that is fun to watch. Buffalo is the better overall team, but the Ravens hold serve at home to come away with the win.
Los Angeles Chargers -5.0 at Houston Texans
Time: 1:00 pm ET
Dunkel Ratings: LA Chargers 130.815; Houston 119.477
Dunkel Line & Total: LA Chargers by 11 ½; 51
Vegas Line & Total: LA Chargers by 5; 44
Dunkel Pick: LA Chargers (-5); Over
The Chargers are 1-2 through three weeks, and they are in desperate need of a win. Los Angeles will be in Houston in Week 4, and this is the perfect time for the Chargers to come away with a blowout win.
Arizona Cardinals at Carolina Panthers (-2.0)
Time: 4:05 pm ET
Dunkel Ratings: Arizona 130.338; Carolina 123.565
Dunkel Line & Total: Arizona by 7; 47
Vegas Line & Total: Carolina by 2; 44
Dunkel Pick: Arizona (+2); Over
The Cardinals and Panthers are both 1-2 on the year, and each team is probably a bit better than that. Arizona will be the better overall team in Week 4 as they come away with a slight upset on the road.
Denver Broncos at Las Vegas Raiders (-2.0)
Time: 4:25 pm ET
Dunkel Ratings: Denver 132.402; Las Vegas 127.841
Dunkel Line & Total: Denver by 4 ½; 29
Vegas Line & Total: Las Vegas by 2; 44
Dunkel Pick: Denver (+2); Under
AFC West rivals meet up when the 0-3 Raiders host the 2-1 Broncos. It’s surprising to see the Raiders without a win year, and they are going to suffer the same fate in Week 4. Take the Broncos to pull off the upset.
New England Patriots at Green Bay Packers (-10.5)
Time: 4:25 pm ET
Dunkel Ratings: New England 132.117; Green Bay 134.987
Dunkel Line & Total: Green Bay by 3; 33
Vegas Line & Total: Green Bay by 10 ½; 40
Dunkel Pick: New England (+10 ½); Under
The Packers host the Patriots on Sunday afternoon for an interesting matchup. This spread is largely based on three weeks of results, and it’s going to be a game that is played pretty tight.
The Packers won’t be able to cover the spread, but they will still pick up their third straight win.
Kansas City Chiefs -2.5 at Tampa Bay Buccaneers
Time: 8:20 pm ET
Dunkel Ratings: Kansas City 147.123; Tampa Bay 129.545
Dunkel Line & Total: Kansas City by 18; 52
Vegas Line & Total: Kansas City by 2 ½; 45
Dunkel Pick: Kansas City (-2 ½); Over
The Sunday Night Football Game will be a rematch of the Super Bowl from two years ago. The Chiefs are road favorites for a good reason in Tampa Bay, and it will be Kansas City that takes control of this game in a blowout win.
Los Angeles Rams at San Francisco 49ers (-2.5)
Time: 8:15 pm ET
Dunkel Ratings: LA Rams 130.971; San Francisco 141.404
Dunkel Line & Total: San Francisco by 10 ½; 46
Vegas Line & Total: San Francisco by 2 ½; 42
Dunkel Pick: San Francisco (-2 ½); Over
The San Francisco 49ers need to make a statement on Monday Night Football, and that is exactly what will happen. Bet the 49ers -2.5 as they play a great game and beat the Rams by double digits.
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All Media on this page by Associated Press.
