Yankees vs. Padres Dunkel MLB Picks, Predictions and Prop Bets - Sept. 4

The New York Yankees and San Diego Padres clash in the first of a three-game series on Friday at Petco Park, at 9:40 p.m. ET. Max Fried (4-4, 2.80 ERA) will start for the Yankees, who are 80-60 this season and second in the AL East. Walker Buehler (8-6, 4.66 ERA) is the expected starter for the Padres, who are 73-67 and third in the NL West.

The moneyline odds for the Yankees (-122) versus the Padres (-101) are tight. The game's over/under is 7.5.

Yankees vs. Padres Odds, Game Time

• Game day: Friday, September 4, 2026
• Game time: 9:40 p.m. ET
• Location: San Diego, California
• Stadium: Petco Park
• Favorite: Yankees (-122)
• Underdog: Padres (-101)
• Over/under: 7.5

How to Watch Yankees vs. Padres

• TV Channel: SDPA and YES
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Yankees vs. Padres: Betting the Moneyline

• The Yankees have been favored on the moneyline 114 total times this season. They've finished 67-47 in those games.
• San Diego has been underdogs in 74 games this season and has come away with the win 35 times (47.3%) in those contests.
• New York is 56-40 this season when entering a game favored by -122 or more on the moneyline.
• This season, the Padres have come away with a win 28 times in 61 chances when named as an underdog of at least -101 or longer on the moneyline.
• The Yankees have an implied moneyline win probability of 55% in this matchup.
• The moneyline set for this matchup implies the Padres have a 50.2% chance of walking away with the win.

Yankees vs. Padres: Betting the Spread & Total

• The Yankees have combined with opponents to go over the total 61 times this season for a 61-75-4 record against the over/under.
• San Diego's games have gone over the total in 62 of its 140 chances.
• The Yankees have put together a 69-71-0 record against the spread this season (covering 49.3% of the time).
• The Padres are 79-61-0 against the spread in their 140 games with a line set by sportsbooks this season.