Yankees vs. Astros Dunkel MLB Picks, Predictions and Prop Bets - April 25

Two of the league's best sluggers face off when the New York Yankees and Houston Astros play at Daikin Park, at 7:10 p.m. ET on Saturday. Ben Rice has nine homers (fourth in league) for the Yankees, and Yordan Alvarez is first with 11 round-trippers for the Astros. Ryan Weathers (1-2, 3.18 ERA) will start for the Yankees, who are 17-9 this season and first in the AL East. Mike Burrows (1-3, 6.75 ERA) is starting for the Astros, who are 10-17 and fifth in the AL West.

Despite playing away from home the Yankees are at -157 to win, compared to the Astros at +132. The game has an over/under set at 9 runs.

Yankees vs. Astros Odds, Game Time

• Game day: Saturday, April 25, 2026
• Game time: 7:10 p.m. ET
• Location: Houston, Texas
• Stadium: Daikin Park
• Favorite: Yankees (-157)
• Underdog: Astros (+132)
• Over/under: 9

How to Watch Yankees vs. Astros

• TV Channel: SCHN and YES
• Live Stream: Fubo (Watch for free)

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Yankees vs. Astros: Betting the Moneyline

• The Yankees have won 15 of the 24 games they were listed as the moneyline favorite this season (62.5%).
• Houston has come away with five wins in the 11 contests it has been listed as the underdogs in this season.
• New York has a record of 8-6 in games when oddsmakers favor them by at least -157 on the moneyline.
• This season, the Astros have been victorious one time in four chances when named as an underdog of at least +132 or worse on the moneyline.
• Based on this matchup's moneyline, the Yankees' implied win probability is 61.1%.
• The Astros have an implied victory probability of 43.1% according to the moneyline set by sportsbooks for this matchup.

Yankees vs. Astros: Betting the Spread & Total

• The Yankees have combined with opponents to hit the over on the total 10 times this season for a 10-14-2 record against the over/under.
• So far this season, Houston and its opponents have hit the over in 19 of its 27 games with a total.
• The Yankees have a 15-11-0 record ATS this season (covering 57.7% of the time).
• In 27 games with a line this season, the Astros have a mark of 10-17-0 against the spread.