Mets vs. Nationals Dunkel MLB Picks, Predictions and Prop Bets - Sept. 21
21 September 2025

The New York Mets host the Washington Nationals at 1:40 p.m. ET on Sunday, with both teams hoping to win the series. Sean Manaea (2-3, 5.40 ERA) will start for the Mets, who are 80-75 this season and second in the NL East. Jake Irvin (8-13, 5.76 ERA) is expected to start for the Nationals, who are 63-92 and fifth in the NL East.
The bookmakers have spoken, making the Mets (-270) a moderate moneyline favorite to defeat the Nationals (+218) at home. The game has an over/under set at 8.5 runs.
Mets vs. Nationals Odds, Game Time
- Game day: Sunday, September 21, 2025
- Game time: 1:40 p.m. ET
- Location: Queens, New York
- Stadium: Citi Field
- Favorite: Mets (-270)
- Underdog: Nationals (+218)
- Over/under: 8.5
How to Watch Mets vs. Nationals
- TV Channel: MASN2 (Washington DC)
- Live Stream: Fubo (Watch for free)
Mets vs. Nationals: Betting the Moneyline
- The Mets have won 62 of the 110 games they were listed as the moneyline favorite this season (56.4%).
- Washington has been pegged as an underdog in 136 games this year and has walked away with the win 57 times (41.9%) in those games.
- New York has entered 13 games this season favored by -270 or more and is 11-2 in those contests.
- The Nationals have a win-loss record of 2-4 when favored by +218 or worse by sportsbooks this year.
- Based on this contest's moneyline, the Mets' implied win probability is 73%.
- The Nationals have an implied victory probability of 31.4% according to the moneyline set for this matchup.
Mets vs. Nationals: Betting the Spread & Total
- The Mets have played in 155 games with set over/under, and have combined with opponents to go over the total 73 times (73-74-8).
- So far this season, Washington and its opponents have hit the over in 77 of its 154 games with a total.
- The Mets have a 71-84-0 record against the spread this season (covering 45.8% of the time).
- The Nationals have an against the spread record of 75-79-0 in 154 games with a line this season.