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Mets vs. Nationals Dunkel MLB Picks, Predictions and Prop Bets - Sept. 21

21 September 2025 By Data Skrive

The New York Mets host the Washington Nationals at 1:40 p.m. ET on Sunday, with both teams hoping to win the series. Sean Manaea (2-3, 5.40 ERA) will start for the Mets, who are 80-75 this season and second in the NL East. Jake Irvin (8-13, 5.76 ERA) is expected to start for the Nationals, who are 63-92 and fifth in the NL East.

The bookmakers have spoken, making the Mets (-270) a moderate moneyline favorite to defeat the Nationals (+218) at home. The game has an over/under set at 8.5 runs.

Mets vs. Nationals Odds, Game Time

  • Game day: Sunday, September 21, 2025
  • Game time: 1:40 p.m. ET
  • Location: Queens, New York
  • Stadium: Citi Field
  • Favorite: Mets (-270)
  • Underdog: Nationals (+218)
  • Over/under: 8.5

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Mets vs. Nationals: Betting the Moneyline

  • The Mets have won 62 of the 110 games they were listed as the moneyline favorite this season (56.4%).
  • Washington has been pegged as an underdog in 136 games this year and has walked away with the win 57 times (41.9%) in those games.
  • New York has entered 13 games this season favored by -270 or more and is 11-2 in those contests.
  • The Nationals have a win-loss record of 2-4 when favored by +218 or worse by sportsbooks this year.
  • Based on this contest's moneyline, the Mets' implied win probability is 73%.
  • The Nationals have an implied victory probability of 31.4% according to the moneyline set for this matchup.

Mets vs. Nationals: Betting the Spread & Total

  • The Mets have played in 155 games with set over/under, and have combined with opponents to go over the total 73 times (73-74-8).
  • So far this season, Washington and its opponents have hit the over in 77 of its 154 games with a total.
  • The Mets have a 71-84-0 record against the spread this season (covering 45.8% of the time).
  • The Nationals have an against the spread record of 75-79-0 in 154 games with a line this season.
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