Andrew Luck had a solid return statistically (385 yards passing and 4 TDs) as QB of the Colts after missing the end of last season with a lacerated kidney. But his effort couldn't help Indianapolis avoid a season-opening loss to the Lions (39-35) at home. Now the Colts have to hit the road to face the defending champion Broncos in Denver. To get our pick for this game and the complete NFL schedule for Week 2, click on the Football icon above. Plus get all our selections for today's MLB, CFL and WNBA slates.