Twins vs. Guardians Dunkel MLB Picks, Predictions and Prop Bets - July 20

The Minnesota Twins and Cleveland Guardians clash on Monday at 6:40 p.m. ET, opening a four-game series at Progressive Field. Joe Ryan (6-5, 3.34 ERA) gets the start for the Twins, who are 49-51 this season and third in the AL Central. Tanner Bibee (3-9, 3.90 ERA) is expected to start for the Guardians, who are 52-48 and second in the AL Central.

Despite being the away team the Twins are a moderate moneyline favorite (-122) over the Guardians (+100). The game has an over/under set at 7.5 runs.

Twins vs. Guardians Odds, Game Time

• Game day: Monday, July 20, 2026
• Game time: 6:40 p.m. ET
• Location: Cleveland, Ohio
• Stadium: Progressive Field
• Favorite: Twins (-122)
• Underdog: Guardians (+100)
• Over/under: 7.5

How to Watch Twins vs. Guardians

• TV Channel: CLEG and MNNT
• Live Stream: Fubo (Watch for free)

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Twins vs. Guardians: Betting the Moneyline

• The Twins have won 19 of the 33 games they were listed as the moneyline favorite this season (57.6%).
• Cleveland has come away with 23 wins in the 44 contests it has been listed as the underdogs in this season.
• Minnesota has a record of 10-7, a 58.8% win rate, when favored by -122 or more by sportsbooks this season.
• This season, the Guardians have been victorious 22 times in 40 chances when named as an underdog of at least +100 or longer on the moneyline.
• Based on this contest's moneyline, the Twins' implied win probability is 55%.
• The Guardians have an implied victory probability of 50% according to the moneyline set by oddsmakers for this matchup.

Twins vs. Guardians: Betting the Spread & Total

• In the 100 games in which oddsmakers have set an over/under for the Twins, they have combined with opponents to go over the total 56 times (56-40-4).
• Cleveland and its opponents have gone over the total this season in 47 of its 100 opportunities.
• The Twins have covered 53% of their games this season, going 53-47-0 against the spread.
• In 100 games with a line this season, the Guardians have a mark of 50-50-0 against the spread.