Marlins vs. Cardinals Dunkel MLB Picks, Predictions and Prop Bets - April 21

The St. Louis Cardinals will look for Jordan Walker to extend a 15-game hitting streak versus the Miami Marlins, on Tuesday at 6:40 p.m. ET, at loanDepot park. Chris Paddack (0-3, 5.59 ERA) gets the start for the Marlins, who are 11-12 this season and second in the NL East. Dustin May (2-2, 6.98 ERA) is expected to start for the Cardinals, who are 13-9 and fourth in the NL Central.

With moneyline odds of -118 for the Marlins and -101 for the Cardinals, this could be a close contest. The game's over/under is set at 8.5.

Marlins vs. Cardinals Odds, Game Time

• Game day: Tuesday, April 21, 2026
• Game time: 6:40 p.m. ET
• Location: Miami, Florida
• Stadium: loanDepot park
• Favorite: Marlins (-118)
• Underdog: Cardinals (-101)
• Over/under: 8.5

How to Watch Marlins vs. Cardinals

• TV Channel: MIAM and CARD
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Marlins vs. Cardinals: Betting the Moneyline

• The Marlins have won 64.3% of the games this season when they were favored on the moneyline (9-5).
• St. Louis has come away with 11 wins in the 19 contests it has been listed as the underdogs in this season.
• Miami has a record of 8-3, a 72.7% win rate, when favored by -118 or more by oddsmakers this season.
• This season, the Cardinals have come away with a win nine times in 16 chances when named as an underdog of at least -101 or longer on the moneyline.
• The Marlins have an implied moneyline win probability of 54.1% in this contest.
• Bookmakers have implied with the moneyline set for this matchup that the Cardinals have a 50.2% chance of pulling out a win.

Marlins vs. Cardinals: Betting the Spread & Total

• The Marlins have played in 23 games with set over/under, and have combined with opponents to go over the total 14 times (14-8-1).
• St. Louis and its opponents have hit the over in 12 of its 22 games with a total this season.
• The Marlins have covered just 39.1% of their games this season, going 9-14-0 ATS.
• The Cardinals have an against the spread mark of 12-10-0 in 22 games with a line this season.