Louisville vs. Pittsburgh Dunkel Predictions & Vegas Odds - Jan. 17

The No. 20 Louisville Cardinals (12-5, 2-3 ACC) visit the Pittsburgh Panthers (8-9, 1-3 ACC) at Petersen Events Center, starting at 8 p.m. ET on Saturday, January 17, 2026. The Cardinals are 7.5-point favorites in the game. The point total in the matchup is 151.5.

Louisville enters this contest on the heels of a 79-70 loss to Virginia on Tuesday. In the losing effort, Isaac McKneely led Louisville with 23 points. In its most recent outing on Wednesday, Pittsburgh claimed an 89-66 victory over Georgia Tech. In Pittsburgh's win, Brandin Cummings led the way with 23 points (adding two rebounds and two assists).

Louisville vs. Pittsburgh Odds and Game Time

• When: Saturday, January 17, 2026 at 8 p.m. ET
• Where: Petersen Events Center in Pittsburgh, Pennsylvania
• Spread favorite: Louisville -7.5
• Moneyline favorite: Louisville -316
• Moneyline underdog: Pittsburgh +253
• Over/Under: 151.5 points

How to watch Louisville vs. Pittsburgh

• TV Channel: ESPN2
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Louisville vs. Pittsburgh

• Louisville and its opponents have hit the over on this game's total (151.5 points) nine times this season.
• This season, six of Pittsburgh's games have finished with a combined score higher than 151.5 points.
• Together, the two teams combine for 161.3 points per game, 9.8 points more than the total of 151.5 for this matchup.
• These two teams surrender a combined 139.6 points per game, 11.9 less than this contest's over/under.
• On average, Louisville has had a 157.4-point over/under in its games this season, 5.9 more points than the over/under in this contest.
• A difference of 8.0 points separates this matchup's over/under (151.5 points) and the average over/under in Pittsburgh's games (143.5) this season.

Betting the Spread: Louisville vs. Pittsburgh

• Louisville has played 17 games, with nine wins against the spread.
• The Cardinals are 7-4 ATS when favored by 7.5 points or more this season.
• Pittsburgh has played 17 games, with eight wins against the spread.
• The Panthers have been underdogs by 7.5 points or more two times this season and covered the spread once.
• Pittsburgh is 5-6 against the spread, and 6-5 overall, at home.
• This year, as a 7.5-point underdog or more at home, Pittsburgh is 4-3 ATS.
• Away from home, Louisville has only one win against the spread and are 1-3 overall.
• Louisville has one win ATS (1-1) on the road as 7.5-point favorites or more.

Betting the Moneyline: Louisville vs. Pittsburgh

• Louisville has entered the game as moneyline favorites 14 times this season and won 11, or 78.6%, of those games.
• The Cardinals have a record of 9-1, a 90% win rate, when favored by -316 or more by bookmakers this season.
• Sportsbooks have implied with the moneyline set for this matchup that Louisville has a 76% chance to win.
• Pittsburgh has come away with two wins in the seven contests it has been listed as the moneyline underdog this season.
• The Panthers have been listed as an underdog of +253 or more on two occasions this season and lost both games.
• The moneyline set for this matchup implies Pittsburgh has a 28.3% chance of coming away with a victory in the contest.