Angels vs. Blue Jays Dunkel MLB Picks, Predictions and Prop Bets - April 22

The Los Angeles Angels will try to snap a four-game losing streak when hosting the Toronto Blue Jays at 3:07 p.m. ET on Wednesday. Jose Soriano (5-0, 0.28 ERA) gets the start for the Angels, who are 11-14 this season and third in the AL West. Eric Lauer (1-3, 7.13 ERA) is the expected starter for the Blue Jays, who are 10-13 and fourth in the AL East.

Bookmakers expect a close matchup between the Angels (-113 to win) and the Blue Jays (-104). The over/under for the Angels-Blue Jays game is set at 9.

Angels vs. Blue Jays Odds, Game Time

• Game day: Wednesday, April 22, 2026
• Game time: 3:07 p.m. ET
• Location: Anaheim, California
• Stadium: Angel Stadium
• Favorite: Angels (-113)
• Underdog: Blue Jays (-104)
• Over/under: 9

How to Watch Angels vs. Blue Jays

• TV Channel: FDSW and SNET
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Angels vs. Blue Jays: Betting the Moneyline

• The Angels have been favored on the moneyline three total times this season. They've gone 2-1 in those games.
• Toronto has won in three of the eight contests it has been named as odds-on underdogs in this year.
• Los Angeles has played as favorites of -113 or more twice this season and split those games.
• The Blue Jays have a mark of 2-5 in contests where oddsmakers favor them by -104 or worse on the moneyline.
• The Angels have a 53.1% chance to win this game based on the moneyline's implied probability.
• The moneyline set for this matchup implies the Blue Jays have a 51% chance of coming away with a victory in the contest.

Angels vs. Blue Jays: Betting the Spread & Total

• The Angels have combined with opponents to go over the total 12 times this season for a 12-12-1 record against the over/under.
• Toronto and its opponents have gone over the total this season in 11 of its 23 opportunities.
• The Angels are 14-11-0 ATS this season.
• The Blue Jays are 8-15-0 against the spread in their 23 games that had a posted line this season.