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Kansas City Chiefs at San Francisco 49ers Betting Preview/Prop Picks

22 October 2022

Time: 4:25 pm ET
Dunkel Ratings: Kansas City 139.552; San Francisco 133.096
Dunkel Line & Total: Kansas City by 6 ½; 52
Vegas Line & Total: Kansas City by 3; 48
Dunkel Pick: Kansas City (-3); Over

Week 7 is full of games that are worth watching, and this one is definitely one of them. With a record of 4-2 this season, the Kansas City Chiefs will face the 3-3 San Francisco 49ers.

There's a lot riding on this game for the Chiefs as they're tied at the top spot in their division. A win here could help them take it over and separate themselves from the Los Angeles Chargers. 

The San Francisco 49ers come into this game with a few different pieces of news. Christian McCaffrey has joined the team after the 49ers traded away several picks.

This could be a big help to the San Francisco offense, which has struggled at times. They'll have four formally injured players back in the lineup tonight as well, so who's the best bet?

 

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Kansas City Chiefs -3 -110

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Kansas City Chiefs: The Chiefs' defense needs to be at its best

Offensively, the Kansas City Chiefs are ranked the best in the NFL. On average, they score 29.8 points per game, the highest in the league. They average 275.8 passing yards per game, ranking fourth overall.

Their running game could use some work, as they only average 106.5 rushing yards per game. Still, the Chiefs' offense is at the top of its game right now.

The problem now is that their defense isn't matching up with their offense. In their loss to the Buffalo Bills, they were unable to stop the Chiefs from scoring with 1:04 remaining.

This resulted in a 24-20 loss for the Kansas City Chiefs. On average, the Chiefs allow 24.8 points per game. With Chrisitan McCaffrey at running back for the 49ers, the Chiefs have a new weapon to watch.

San Francisco 49ers: Getting an early lead is the key to a win

The San Francisco 49ers are known for having a stout defense, but this time they'll need offense. So far this season, the 49ers haven't been great at putting points on the board.

They've averaged just 20.3 points per game, ranking 20th overall in the league. Considering they're playing one of the best offenses in the league, they'll need to find ways to score. 

We're not sure how large of a role Christian McCaffrey will play in this game. He's only joined the team this week, and likely doesn't know the playbook very well.

The good news is he's not a quarterback, so it won't be nearly as complicated for him. The 49ers are also backed up by a strong defense that allows just 14.8 points per game.

Kansas City Chiefs vs. San Francisco 49ers Betting Pick

This game is a pretty complicated one to call because of what each team brings to the matchup. On one side, you have the 49ers, who have one of the best defenses in the league.

On the other, you have the Chiefs, who are notorious for scoring a lot of points against any defense. The main problem for the 49ers, however, is their own offense.

Averaging just 20.3 points per game won't work against the Chiefs. Kansas City's defense, which isn't good, has shown some resiliency at times.

Holding the Buffalo Bills to just 24 points is pretty impressive. Since they only need to cover three points, the Chiefs are our pick to win this game on the road.

DunkelIndex Free Pick: Kansas City Chiefs -3, OVER

Prop Picks

Kansas City (-145) OVER 2.5 Team Total Touchdowns

Kansas City is averaging 29.8 points per game on offense, which ranks No. 1 in the NFL. That average increases to 34.0 points per game on the road. Scores have gone OVER in 10 of the Chiefs’ last 14 games overall.

With Dunkel predicting a Kansas City victory by the score of 29-23, take the Chiefs (-145) to finish OVER their Vegas total of 2.5 team touchdowns versus the 49ers.

Jimmy Garappolo (-115) OVER 251.5 Passing Yards

Kansas City is allowing 266.0 passing yards per game on defense, which ranks No. 27 in the NFL. That average increases to 304.7 yards per game over the last 3 games.

With Dunkel predicting the final score going OVER the Vegas point total, take Garoppolo (-115) to finish OVER 251.5 passing yards against the Chiefs.

Keep up with your latest NFL news coverage and betting pick previews at The Dunkel Index.

All Media on this page by Associated Press.

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