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Astros vs. Cardinals Dunkel MLB Picks, Predictions and Prop Bets - April 19

19 April 2026 By Data Skrive

The St. Louis Cardinals will look to Jordan Walker, riding a 13-game hitting streak, versus the Houston Astros at 2:10 p.m. ET on Sunday, at Daikin Park. Mike Burrows (1-3, 6.55 ERA) will start for the Astros, who are 8-14 this season and fifth in the AL West. Matthew Liberatore (0-1, 4.29 ERA) is expected to start for the Cardinals, who are 12-8 and third in the NL Central.

Sportsbooks have made the Astros a decent moneyline favorite (-149) at home over the Cardinals (+125). The contest has an over/under set at 8.5.

Astros vs. Cardinals Odds, Game Time

  • Game day: Sunday, April 19, 2026
  • Game time: 2:10 p.m. ET
  • Location: Houston, Texas
  • Stadium: Daikin Park
  • Favorite: Astros (-149)
  • Underdog: Cardinals (+125)
  • Over/under: 8.5

How to Watch Astros vs. Cardinals

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Astros vs. Cardinals: Betting the Moneyline

  • The Astros have won 33.3% of the games this season when they were the moneyline favorite (5-10).
  • St. Louis has won in 10, or 58.8%, of the 17 contests it has been named as odds-on underdogs in this year.
  • Houston has a record of 3-5 when favored by -149 or more by bookmakers this season.
  • This season, the Cardinals have been victorious one time in four chances when named as an underdog of at least +125 or worse on the moneyline.
  • Based on this contest's moneyline, the Astros have an implied win probability of 59.8%.
  • The Cardinals have an implied victory probability of 44.4% according to the moneyline set by oddsmakers for this matchup.

Astros vs. Cardinals: Betting the Spread & Total

  • The Astros have played in 22 games with an over/under set, and have combined with their opponents to go over the total 15 times (15-7-0).
  • St. Louis' games have gone over the total in 11 of its 20 chances.
  • The Astros have gone 8-14-0 ATS this season.
  • In 20 games with a line this season, the Cardinals have a mark of 11-9-0 against the spread.
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