Astros vs. Marlins Dunkel MLB Picks, Predictions and Prop Bets - July 22

The Houston Astros will look to Jeremy Pena, currently on a two-game homer streak, against the Miami Marlins at 8:10 p.m. ET on Wednesday, at Daikin Park. Peter Lambert (8-5, 3.03 ERA) will start for the Astros, who are 49-54 this season and third in the AL West. Sandy Alcantara (10-5, 3.89 ERA) is starting for the Marlins, who are 52-50 and third in the NL East.

The moneyline odds for the Astros (-120) versus the Marlins (-101) are tight. The contest has a total set at 8.

Astros vs. Marlins Odds, Game Time

• Game day: Wednesday, July 22, 2026
• Game time: 8:10 p.m. ET
• Location: Houston, Texas
• Stadium: Daikin Park
• Favorite: Astros (-120)
• Underdog: Marlins (-101)
• Over/under: 8

How to Watch Astros vs. Marlins

• TV Channel: SCHN and MIAM
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Astros vs. Marlins: Betting the Moneyline

• The Astros have a 17-21 record in games they were favored on the moneyline (winning 44.7% of those games).
• Miami has been underdogs in 54 games this season and has come away with the win 20 times (37%) in those contests.
• This season Houston has won 13 of its 31 games, or 41.9%, when favored by at least -120 on the moneyline.
• This year, the Marlins have won 18 of 46 games when listed as at least -101 or worse on the moneyline.
• The Astros have a 54.5% chance to win this matchup based on the moneyline's implied probability.
• The Marlins have an implied victory probability of 50.2% according to the moneyline set by sportsbooks for this matchup.

Astros vs. Marlins: Betting the Spread & Total

• The Astros have had an over/under set by oddsmakers 103 times, and have combined with opponents to go over the total in 53 of those games (53-44-6).
• Miami's games have gone over the total in 53 of its 102 chances.
• The Astros have collected a 51-52-0 record against the spread this season.
• In 102 games with a line this season, the Marlins have a mark of 52-50-0 against the spread.