Astros vs. Diamondbacks Dunkel MLB Picks, Predictions and Prop Bets - Sept. 5

The Houston Astros host the Arizona Diamondbacks at 7:15 p.m. ET on Saturday, a game featuring two of the league's most consistent hitters. Yordan Alvarez has an average of .316 (first in league) for the Astros, while Gabriel Moreno ranks eighth at .298 for the Diamondbacks. Ethan Pecko (1-0, 6.23 ERA) gets the start for the Astros, who are 73-69 this season and first in the AL West. Brandon Pfaadt (7-2, 3.49 ERA) is starting for the Diamondbacks, who are 74-68 and third in the NL West.

The Diamondbacks (+108) take their show on the road to face the favored Astros (-132). The contest has a total set at 8.5.

Astros vs. Diamondbacks Odds, Game Time

• Game day: Saturday, September 5, 2026
• Game time: 7:15 p.m. ET
• Location: Houston, Texas
• Stadium: Daikin Park
• Favorite: Astros (-132)
• Underdog: Diamondbacks (+108)
• Over/under: 8.5

How to Watch Astros vs. Diamondbacks

• TV Channel: FOX
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Astros vs. Diamondbacks: Betting the Moneyline

• The Astros are 31-30 in games they were favored on the moneyline (winning 50.8% of those games).
• Arizona has come away with 38 wins in the 82 contests it has been listed as the underdogs in this season.
• Houston has a record of 18-19, a 48.6% win rate, when favored by -132 or more by bookmakers this season.
• This year, the Diamondbacks have won 27 of 57 games when listed as at least +108 or worse on the moneyline.
• The Astros have a 56.9% chance to win this game based on the moneyline's implied probability.
• The moneyline set for this matchup implies the Diamondbacks have a 48.1% chance of coming away with a victory in the contest.

Astros vs. Diamondbacks: Betting the Spread & Total

• The Astros have combined with opponents to hit the over on the total 71 times this season for a 71-62-9 record against the over/under.
• Arizona's games have gone over the total in 62 of its 142 chances.
• The Astros have collected a 73-69-0 record against the spread this season (covering 51.4% of the time).
• The Diamondbacks are 78-64-0 against the spread in their 142 games that had a posted line this season.