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Golden Knights vs. Blues NHL Predictions, Picks and Odds - Oct. 22

22 October 2026 By Data Skrive

The Vegas Golden Knights (8-3) visit the St. Louis Blues (4-4-1) on Thursday, Oct. 22, with the Golden Knights coming off a defeat in their last game and the Blues a victory. Golden Knights (-125) at Blues (+105) has a clear favorite, according to the moneyline odds.

Vegas fell 6-2 at home its last time out on Oct. 20 against the Tampa Bay Lightning. The Golden Knights got one point apiece out of four players, including Mark Stone (one goal) and Mitchell Marner (one assist).

St. Louis won its last game 2-1 at home against the Winnipeg Jets on Oct. 20. Philip Broberg's two points (one goal and one assist) in that matchup led the Blues.

As hockey play continues, prepare for the matchup by checking out which team we predict will win Thursday's game.

Bet now on FanDuel Sportsbook!

Golden Knights vs. Blues Predictions & Pick

For the upcoming contest between the Vegas Golden Knights and St. Louis Blues, computer-calculated moneyline, over/under, and score predictions are below, per Dunkel Index.

  • Prediction: Golden Knights 2 - Blues 1
  • Pick OU: Under 6.5 (Dunkel projecting 3 goals)

Pick with the best in the business! Get free picks for every game, every week at the Dunkel Index.

Golden Knights vs. Blues Moneylines

Take a look below at the latest moneylines for the Golden Knights-Blues matchup.

  • Favorite: Golden Knights (-125)
  • Underdog: Blues (+105)

Golden Knights Betting Insights

  • The Golden Knights have won 88.9% of their games when they've been a moneyline favorite this season (8-1).
  • Vegas is 8-1 (winning 88.9% of its games) when it has played with moneyline odds of -125 or shorter.
  • The implied moneyline probability in this game says the Golden Knights have a 55.6% chance to win.
  • Vegas' 11 matches this season have finished above this game's total of 6.5 goals eight times.

Blues Betting Insights

  • This season the Blues have been an underdog three times, and won one of those games.
  • St. Louis has a record of 1-2 in games when sportsbooks have them as underdogs of at least +105 on the moneyline.
  • The Blues have a 48.8% chance to win this game based on the implied probability of the moneyline.
  • St. Louis' games this season have had more than 6.5 goals five of nine times.

Golden Knights Key Stats

  • Vegas leads the NHL with 43 total goals (3.9 per game).
  • The Golden Knights rank 18th in goals against, giving up 30 total goals (2.7 per game) in NHL play.
  • Its +13 goal differential is the fourth-best in the league.
  • The 10 power-play goals the Golden Knights have put up this season (third-most in the NHL) have come on 40 power-play chances.
  • Vegas' 25% power-play conversion rate is the seventh-best in the league.
  • The Golden Knights have scored three shorthanded goals this season to pace the NHL.
  • Vegas kills 73.08% of opponent power plays, the 24th-ranked penalty-kill percentage in the league.
  • Vegas has the 13th-ranked faceoff win rate in the NHL, at 51.3%.
  • The Golden Knights connect on 13% of their shots (sixth in the league).

Blues Key Stats

  • With 29 goals (3.2 per game), St. Louis has the league's 16th-ranked offense.
  • The Blues allow 3.2 goals per game (29 in total), 14th in the NHL.
  • Its 0 goal differential ranks 18th in the league.
  • The Blues have five power-play goals (on 26 chances), 21st in the NHL.
  • St. Louis scores on 19.23% of its power plays, No. 21 in the league.
  • The Blues have a league-leading three shorthanded goals.
  • The 85.71% penalty-kill percentage of St. Louis is sixth in the league.
  • At 48.8%, St. Louis has the NHL's 21st-ranked faceoff win rate.
  • The 12.3% shooting percentage of the Blues is 11th in the league.

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